Older Americans Independence Center

美国老年人独立中心

• 批准号: 6785670
• 负责人: LINDA P FRIED
• 金额: $ 16.26万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6785670
• 关键词: biomedical facility; clinical research; disease /disorder etiology; frail elderly; geriatrics; quality of life

DESCRIPTION (provided by applicant): This proposal seeks to establish an Older Americans Independence Center at the Johns Hopkins Medical Institutions. The focus of this center is to promote independence for frail older adults through the development of interventions to prevent or ameliorate frailty and the many serious, adverse outcomes that frail older adults are at risk for. To accomplish this, a multidisciplinary group of senior and junior investigators, in multiple Departments and Programs at this institution, propose to implement, through this OAIC, 1. the leadership group that will stimulate, lead and sustain a University-wide interdisciplinary research program investigating frailty, its etiology and opportunities for treatment; 2. the infrastructure and methodologic development essential to creating the next generations of research on frailty in older adults; 3. to support the career development of outstanding junior faculty committed to research careers that will lead to treatments for frailty and its prevention; and 4. to cultivate and support pilot studies that will provide the basis for investigator-initiated and funded research on frailty over the long run. The OAIC would provide the support critical to organizing the substantial strengths already at this institution into a unified and potent effort directed at developing interventions for frailty. It is designed to ensure multidisciplinary translation between basic and clinical/population-based research, and of both into development of treatments for frailty. This organized infrastructure and scientific leadership can serve as a source of advice and collaborations to investigators at our own institution and at other institutions in the area of research on frailty in aging. The OAIC will be administratively led by, and housed in, the Johns Hopkins Center on Aging and Health, with strong leadership and participation by all of the institutional programs committed to aging research; it will also incorporate leaders and investigators not previously involved in research on frailty but who have made a commitment to this work through the planning process for this proposal. This OAIC has strong institutional commitment, based on the priority at the Medical Institutions for the unification and strengthening of aging research and spotlighting its importance for the entire institution. Overall, it is designed to spearhead a new depth and intensity of research to improve outcomes and promote independence for frail, older adults.

描述（由申请人提供）：该提案旨在在约翰·霍普金斯医疗机构建立一个美国老年人独立中心。该中心的重点是通过制定干预措施来预防或改善体弱以及体弱老年人面临的许多严重不良后果的干预措施，从而促进体弱老年人的独立性。为了实现这一目标，该机构多个部门和项目的高级和初级研究人员组成的多学科小组建议通过 OAIC 实施： 1. 领导小组将刺激、领导和维持全校范围内的跨学科研究项目，调查衰弱及其病因和治疗机会； 2. 对于开展下一代老年人衰弱研究至关重要的基础设施和方法开发； 3. 支持致力于研究事业的优秀青年教师的职业发展，从而治疗和预防衰弱； 4. 培育和支持试点研究，为研究者发起和资助的长期衰弱研究提供基础。 OAIC 将提供至关重要的支持，以将该机构现有的强大优势组织起来，形成统一而有力的努力，旨在制定针对虚弱的干预措施。它旨在确保基础研究和临床/人群研究之间的多学科转化，并将两者转化为衰弱治疗的开发。这种有组织的基础设施和科学领导力可以为我们自己的机构和其他机构在衰老衰弱研究领域的研究人员提供建议和合作。 OAIC 将由约翰霍普金斯大学老龄化与健康中心行政领导并设在该中心，所有致力于老龄化研究的机构项目都将得到强有力的领导和参与；它还将包括以前未参与衰弱研究但在该提案的规划过程中承诺开展这项工作的领导者和研究人员。该 OAIC 具有强有力的机构承诺，基于医疗机构统一和加强老龄化研究的优先事项，并强调其对整个机构的重要性。总体而言，它旨在引领新的深度和强度的研究，以改善结果并促进体弱老年人的独立性。