Appropriate Use of Oral Antibiotics in Children

儿童适当使用口服抗生素

• 批准号: 6707154
• 负责人: HOWARD BAUCHNER
• 金额: $ 14.24万
• 依托单位: BOSTON MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6707154
• 关键词: antibiotics; chemotherapy; child (0-11); children; clinical research; ethnic group; human subject; human therapy evaluation; infant human (0-1 year); oral administration; otitis media; patient oriented research; therapy compliance

DESCRIPTION (provided by applicant): Howard Bauchner, M.D., Professor of Pediatrics and Public Health at Boston University School of Medicine (BUSM), is applying for a Midcareer Investigator Award in Patient-Oriented Research (K24). Dr. Bauchner completed his post-residency training as a Robert Wood Johnson Foundation General Pediatric Academic Fellow at Yale-New Haven in 1986. He joined the faculty at BUSM that year, was promoted to Associate Professor in 1990 and Professor in 1997. Dr. Bauchner's career has been committed to conducting patient-oriented research, and mentoring fellows and faculty in general pediatrics. His own research has focused on randomized controlled trials, methodologic reviews, and therapeutic trials in the areas of sleep, painful procedures, inappropriate oral antibiotic use, and iron deficiency anemia. He has published 60 peer-reviewed articles, and over the past five years conducted six studies in the area of inappropriate oral antibiotic use. Currently, with support from GlaxoSmithKline, he is beginning a practice-based research project in which 12 practices will be randomized to information about the appropriate antibiotics therapy or appropriate diagnosis of acute otitis media (AOM). In this study, it is estimated that 3600 children less than three years of age will be enrolled. The goal is to determine if children with AOM treated with appropriate antibiotics do better than children treated with inappropriate antibiotics. With support from the Maternal and Child Health Bureau, he is also conducting a randomized controlled trial that is focused on increasing the percentage of low-income and minority mothers who breastfeed their premature infants. In addition to his own research efforts, Dr. Bauchner is Project Director of an Institutional National Research Service Award and Faculty Development Program. With support from these two programs, four fellows have been in training each year for the past eight years. These fellows all require intensive mentoring and are conducting patient-oriented research. With support from this program, Dr. Bauchner will commit 50% effort to conducting patient-oriented research and mentoring. He will expand his mentoring efforts to include fellows and faculty in the Divisions of Pediatric Emergency Room Services, Child Development and Adolescent Medicine, and become a senior advisor to the CREST Program (K30) at BUSM.

描述（由申请人提供）：Howard Bauchner，医学博士，波士顿大学医学院（BUSM）儿科和公共卫生教授，正在申请面向患者研究（K24）的职业中期研究者奖。1986年，Bauchner博士作为耶鲁-纽黑文的Robert Wood Johnson基金会普通儿科学术研究员完成了他的住院医师后培训。同年，他加入了BUSM，并于1990年晋升为副教授，1997年晋升为教授。Bauchner博士的职业生涯一直致力于开展以患者为导向的研究，并指导普通儿科的研究员和教师。他自己的研究主要集中在随机对照试验、方法学回顾和睡眠、疼痛过程、不适当的口服抗生素使用和缺铁性贫血等领域的治疗试验。他发表了60篇同行评议的文章，并在过去五年中进行了六项关于口服抗生素使用不当的研究。目前，在葛兰素史克公司（GlaxoSmithKline）的支持下，他正在启动一项基于实践的研究项目，在该项目中，12种实践将被随机分配到有关适当抗生素治疗或适当诊断急性中耳炎（AOM）的信息中。在这项研究中，估计将有3600名3岁以下的儿童被纳入。目的是确定接受适当抗生素治疗的AOM儿童是否比接受不适当抗生素治疗的儿童表现更好。在妇幼卫生局的支持下，他还在进行一项随机对照试验，重点是提高低收入和少数民族母亲母乳喂养早产儿的比例。除了他自己的研究工作，Bauchner博士还是机构国家研究服务奖和教师发展计划的项目主管。在这两个项目的支持下，在过去的八年里，每年有四名研究员接受培训。这些研究员都需要密集的指导，并进行以患者为导向的研究。在该项目的支持下，Bauchner博士将投入50%的精力进行以患者为导向的研究和指导。他将扩大他的指导工作，包括儿科急诊室服务、儿童发展和青少年医学部门的研究员和教师，并成为BUSM CREST项目（K30）的高级顾问。