Center for Environment and Mammary Gland Development

环境与乳腺发育中心

• 批准号: 6805167
• 负责人: JOSE RUSSO
• 金额: $ 154.5万
• 依托单位: FOX CHASE CANCER CENTER
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-29 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6805167
• 关键词: breast neoplasms; clinical research; cooperative study; environment related neoplasm /cancer; environmental exposure; human puberty; nutrition related neoplasm /cancer

The Fox Chase Cancer Center in Philadelphia, Pennsylvania, the University of Alabama Comprehensive Cancer Center in Birmingham, Alabama, and the Mount Sinai School of Medicine in New York, New York, have joined efforts for organizing a Breast Cancer and the Environment Research Center. Researchers at the three participating institutions have a long-lasting commitment to breast cancer research, demonstrated through pioneer work that has identified critical windows of susceptibility to carcinogenic and environmental exposures. The unique experience of this multi-institutional and multi-disciplinary group will provide a broad and comprehensive armarmentarium encompassing varied populations, clinical and basic sciences, and bioinformatics expertise that will be immediately translated to the population it will serve through carefully orchestrated programs under the guidance of patient advocates. The Breast Cancer and the Environment Research Center proposed here will be named Center for the Study of the Environment and Mammary Gland and Development. The Center is organized around two research projects, the Collaborative Project 1 (CP 1) and Collaborative Project 2 (CP 2), and two cores, the Administrative Core and the Community Outreach and Translation Core (COTC). The Administrative Core will serve as a liaison with the Steering Committee of the Breast Cancer and the Environment Research Center Consortium, the Breast Cancer and the Environment Task Force and the National Advisory Board. In addition, there will be an Executive Committee, which will be chaired by the Principal Investigator and will be integrated by the Co-Principal Investigators and one Cancer Advocate. The Executive Committee will receive advice from the Internal and the External Advisory Boards. The Executive Committee will meet on regular basis with the Co-PIs and investigators participating in CP 1 and CP 2, as well as with Members of the Administrative Core and the COTC. Consequently, the chain of authority for the Center grant will start from the Principal Investigator who will provide scientific leadership for all aspects of the Center. These lines of authority will not interfere with the internal chain of authority at each one of the participating institutions. The mission of the Center will be accomplished through interactive meetings among the participants of the Center, and other centers participating in this consortium.

宾夕法尼亚州费城的福克斯·蔡斯癌症中心、亚拉巴马伯明翰的亚拉巴马大学综合癌症中心和纽约纽约的西奈山医学院共同努力组织一个乳腺癌和环境研究中心。 三个参与机构的研究人员对乳腺癌研究有着长期的承诺，这一承诺通过先驱工作得到了证明，这些工作已经确定了致癌物和环境暴露敏感性的关键窗口。 这个多机构和多学科小组的独特经验将提供一个广泛而全面的armarmentarium，包括不同的人群，临床和基础科学以及生物信息学专业知识，这些专业知识将立即转化为人口，它将通过精心策划的计划在患者倡导者的指导下服务。 乳腺癌与环境研究中心将被命名为环境与乳腺发育研究中心。 该中心围绕两个研究项目，合作项目1（CP 1）和合作项目2（CP 2），以及两个核心，行政核心和社区外展和翻译核心（COTC）。 行政核心将作为乳腺癌和环境研究中心联合会指导委员会、乳腺癌和环境工作队和国家咨询委员会的联络机构。 此外，还将成立一个执行委员会，由主要研究者担任主席，并由共同主要研究者和一名癌症倡导者组成。 执行委员会将听取内部和外部咨询委员会的建议。 执行委员会将定期与参与国家方案1和国家方案2的共同首席执行官和调查员以及行政核心和COTC成员举行会议。 因此，中心赠款的权力链将从主要研究者开始，主要研究者将为中心的各个方面提供科学领导。 这些职权范围不会干扰每一个参与机构的内部权力链。 该中心的使命将通过该中心参与者以及参与该联盟的其他中心之间的互动会议来完成。