Center for Prevention and Early Intervention

描述（申请人提供）：这一拟议中的高级干预和服务研究中心“预防和早期干预中心”代表了约翰霍普金斯大学彭博公共卫生学院与我们在预防和早期干预方面的社区合作伙伴之间的合作努力（巴尔的摩市公立学校系统和马里兰州教育部），以及摩根州立大学、宾夕法尼亚州立大学、洛杉矶的加州大学、亚拉巴马大学、哥伦比亚大学和斯坦福大学的预防和早期干预研究人员。 该中心的总体使命是开展方法研究、试点研究和可行性研究，以支持评估旨在减少儿童攻击/破坏行为的循证预防和早期干预措施的有效性。该中心计划制定并随后评估小学环境中预防和早期干预综合方法的有效性。这一综合办法的特点是在一项普遍预防性干预措施中嵌套适用的干预措施和治疗性干预措施。该中心的具体目标是：（1）建立必要的基础设施，成为学术/社区合作的典范;（2）通过统计和经济方法发展方面的进步，改进以学校为基础的有效性研究的设计和分析;（3）进行试点和可行性研究，为该中心干预和评估举措的有效性试验做准备;传播在上述每个领域获得的知识，以改进预防和早期干预研究。 该中心由4个核心组成。运营核心在以下领域为中心合作者提供支持：管理，评估，数据管理以及传播和培训。研究方法核心侧重于生物统计和经济方法的开发和应用，以支持该中心的干预和评估举措。主要研究核心为试点和可行性研究提供结构和支持，旨在为基于小学的循证预防和早期干预及评估的有效性试验奠定基础。 研究网络发展核心的重点是发展巴尔的摩市公立学校系统和马里兰州教育部的基础设施，以开展最先进的预防和早期干预研究和评估。 这四个核心将以一体化的方式工作，以确保实现中心的目标。

DESCRIPTION (provided by applicant): This proposed Advanced Center For Interventions And Services Research "The Center for Prevention and Early Intervention", represents a collaborative effort between the Johns Hopkins University Bloomberg School of Public Health, our community partners in prevention and early intervention (the Baltimore City Public Schools System and the Maryland State Department of Education), and prevention and early intervention researchers at Morgan State University, Pennsylvania State University, the University of California at Los Angeles, the University of Alabama, Columbia University, and Stanford University. The overall mission of the Center is to carry out methodological and pilot and feasibility research to support evaluations of the effectiveness of evidence-based preventive and early interventions aimed at the reduction of aggressive/disruptive behavior in children. The Center plans to develop and subsequently evaluate with the effectiveness of an integrated approach to prevention and early intervention in the elementary school setting. This integrated approach features the nesting of indicated and treatment interventions within a universal preventive intervention. The specific aims of the Center are to: 1) Establish the infrastructure necessary to be a model of academic/community collaboration; 2) Improve the design and analysis of school-based, effectiveness studies through advances in statistical and economic methods development; 3) Conduct pilot and feasibility studies in preparation for effectiveness trials of the Center's intervention and assessment initiatives; and 4) Disseminate the knowledge gained in each of the above areas in order to improve prevention and early intervention research. The Center consists of 4 Cores. The Operations Core provides support to Center collaborators across the Cores in the areas of: administration, assessment, data management, and dissemination and training. The Research Methods Core is focused on the development and application of biostatistical and economic methods in support of the Center's intervention and assessment initiatives. The Principal Research Core provides the structure and support for pilot and feasibility studies aimed at setting the stage for elementary school-based, effectiveness trials of evidence-based prevention and early interventions and assessments. The Research Network Development Core focuses on the development of the infrastructure within the Baltimore City Public School System and the Maryland State Department of Education for carrying out state of the art prevention and early intervention research and evaluations. These 4 Cores will work in an integrated fashion to insure the realization of the Centers' aims.