Tissue Engineering Design of Novel Bio-Therapeutics for Cancer Treatment

癌症治疗的一个新想法是利用组织工程来阻止肿瘤的生长和癌症扩散的进展，例如，通过创造一个生物贴片来包裹肿瘤，从而防止任何进一步的生长或转移。通过仔细考虑要使用的条件和材料，可以创造出可以控制肿瘤形状和大小的支架，并且有可能被设计成包含一系列生物分子，如生长因子和蛋白质。这个想法可以进一步发展成为一种潜在的药物输送方法，通过在工程贴片中添加抗癌药物，这样它不仅可以阻止肿瘤进一步生长，还可以直接将药物输送到肿瘤部位。如果成功，这将为癌症治疗提供急需的突破，直接针对肿瘤并减少与当前治疗相关的令人不快的副作用。与目前的二维细胞研究相比，它还将提供对肿瘤环境更准确的三维洞察，而二维细胞研究是肿瘤环境的不准确表示。

One novel idea for a cancer therapeutic is to use tissue engineering to stop tumour growth and progression of the cancer as it spreads, for example, through creation of a biological patch which can encapsulate the tumour, thus preventing any further growth or metastasis. By careful consideration of the conditions and materials to be used, scaffolds can be created that could control the shape and size of the tumour, and which have potential to be designed to incorporate a range of biomolecules such as growth factors to proteins. This idea could be further developed into a potential method for drug delivery by adding an anti-cancer drug to the engineered patch so that it would not only prevent further tumour growth but also deliver the drug directly to the tumour site. If successful, this could provide a much-needed breakthrough in cancer treatment, with direct targeting of the tumour and reducing the unpleasant side effects associated with current therapeutics. It would also offer a more accurate three-dimensional insight into the tumour environment, compared to current studies which look at two-dimensional cell studies, which are an inaccurate representation of the tumour environment.