THE TREATMENT OF EATING DISORDERS

这是一个独立的科学家奖（K 02）的建议，以支持我在饮食失调的治疗和结果领域的研究计划。这一直是我的工作重点，因为在1992年完成住院医师，自1995年以来，我一直是一个积极的和富有成效的研究小组的主要研究者，专注于饮食失调的治疗和结果的问题。申请围绕R 01赠款“阶梯式护理与神经性贪食症的最佳护理”（R 01-MH-59304）。这是一项为期五年的研究（现在是第三年），研究使用不同顺序的自助，药物治疗和认知行为治疗来治疗神经性贪食症。除了测量这些不同治疗方法的疗效外， 包，成本效益也将衡量。明尼苏达大学精神病学系对该奖项做出了强有力的机构承诺。该部门为研究活动提供了强有力的行政支持和高度支持的环境，最近完成了一个4000平方英尺的精神病学门诊研究中心（ARC）的建设，该中心容纳了我正在进行的研究活动。如果获得资助，该奖项将使我从大量的临床职责中解放出来，并保护我75%的时间用于研究活动。这 增加的时间将允许进行成本效益分析方面的高级专业培训，通过明尼苏达大学临床结果研究中心进行复杂临床结果研究技术方面的专门培训，与B积极协商有关艾德治疗研究问题。蒂莫西沃尔什，医学博士和积极咨询进食障碍的过程和结果研究问题与克里斯托弗费尔伯恩，医学博士。这些职业发展活动将使我能够利用明尼苏达州独特的研究人群和数据，在研究有效和具有成本效益的饮食失调治疗方法并检查其课程和成本方面实现我的研究目标。许多研究计划在这个奖项，并在随后的几年里，利用这些新的技能和独特的资源。

This proposal for an independent Scientist Award (K02) to support my research program in the area of the treatment and outcome of eating disorders. This has been the focus of my work since finishing residency in 1992 and since 1995 I have been the principal investigator of an active and productive research group focused on eating disorders treatment and outcome issues. The application centers around R01 grant "Stepped Care vs. Best Available care for Bulimia Nervosa" (R01-MH-59304). This is a five year study (now in its third year) examining the use of different sequences of self-help, pharmacotherapy, and cognitive behavioral therapy to treat bulimia nervosa. In addition to measuring the efficacy of these various treatment packages, cost efficacy will also be measured. The Department of Psychiatry at the University of Minnesota has made a strong institutional commitment to this award. The department provides strong administrative support and a highly supportive environment for research activities, and recently completed construction of a 4000 square feet Psychiatry Ambulatory Research Center (ARC) that houses my ongoing research activities. If funded, this award will free me up from substantial clinical duties and protect fully 75% of my time for research activities. This increased time will allow for advanced specialized training in cost efficacy analysis, specific training in sophisticated clinical outcomes research techniques through the Clinical Outcomes Research Center at the University of Minnesota, active consultation regarding ED treatment study issues with B. Timothy Walsh, M.D and active consultation on eating disorder course and outcome study issues with Christopher Fairbum, M.D. These career development activities will enable me to utilize the unique research populations and data available at Minnesota to pursue my research goals in the areas of studying effective and cost effective treatment for eating disorders and examining their course and their costs. Numerous studies are planned during this award and in the years that follow to leverage these new skills and unique resources.