Gordon Research Conference: Lipoprotein Metabolism 2004

描述(由申请人提供)： 本申请是对2004年戈登脂蛋白代谢研究会议的部分支持，会议将于2004年6月13日至28日在新罕布夏州梅里登的金博尔联合学院举行。会议的题目是《脂类和脂蛋白代谢的细胞和分子调控》。本次会议将聚焦于脂和脂蛋白代谢方面的重要新进展，特别是那些影响人类代谢性疾病和动脉粥样硬化性血管疾病发展的领域。将介绍基础分子和细胞生物学研究以及在人类和动物模型中的活体研究。主题将包括人类遗传的脂蛋白代谢，高密度脂蛋白代谢，脂合成和运输，核受体，脂肪细胞脂代谢，细胞信号和脂毒性。计划举办九场会议，内容包括：1.人类脂蛋白代谢遗传学2.高密度脂蛋白结构和新陈代谢3.核受体和脂类代谢4.脂类合成和运输5.脂肪细胞脂类代谢的调节6.通过脂蛋白受体传递细胞信号7.主讲人：Ronald Evans--脂类代谢和动脉粥样硬化中的核受体8.巨噬细胞脂代谢和炎症9.细胞脂毒性这次会议将是介绍和整合脂蛋白和脂代谢最新发展的主要载体。重点将放在对新的、基本上未发表的研究进行深入介绍和彻底讨论上。戈登脂蛋白代谢研究会议的重要目标是包括合格专业人员的多样性，并促进年轻研究人员、博士后研究员、研究生和高级研究人员之间的互动。

DESCRIPTION (provided by applicant): This application is for partial support of the 2004 Gordon Research Conference on Lipoprotein Metabolism to be held at Kimball Union Academy in Meriden, New Hampshire on June 13-28, 2004. The title of the conference is "Cellular and Molecular Regulation of Lipid and Lipoprotein Metabolism." This conference will focus on important new developments in lipid and lipoprotein metabolism, particularly in those areas that impact on human metabolic disease and the development of atherosclerotic vascular disease. Basic molecular and cell biological studies and in vivo studies in humans and animal models will be presented. Topics will include human genetics of lipoprotein metabolism, high density lipoprotein metabolism, lipid synthesis and transport, nuclear receptors, adipocyte lipid metabolism, cellular signaling, and lipotoxicity. Nine sessions are planned and will cover: 1. Human Genetics of Lipoprotein Metabolism 2. HDL Structure and Metabolism 3. Nuclear Receptors and Lipid Metabolism 4. Lipid synthesis and transport 5. Regulation of adipocyte lipid metabolism 6. Cellular signaling via lipoprotein receptors 7. Keynote Speaker: Ronald Evans--Nuclear receptors in lipid metabolism and atherosclerosis 8. Macrophage lipid metabolism and inflammation 9. Cellular lipotoxicity This conference will be a major vehicle for the presentation and integration of the latest developments in lipoprotein and lipid metabolism. Emphasis will be placed on in-depth presentations and thorough discussions of new, largely unpublished studies. Important aims of the Gordon Research Conference on Lipoprotein Metabolism are to include the diversity of qualified professionals and to foster interactions among young investigators, post-doctoral fellows, graduate students, and senior investigators.