Complex Trait Consortium 2004, 3rd Annual Conference

描述(申请人提供)：此申请是为了支持将于7月6-9日在缅因州巴尔港的杰克逊实验室(TJL)举行的“复杂特征联盟2004，第三届年会”。复杂性状联合会(CTC)会议的目标是将对实验室小鼠的开发和使用作为了解人类健康和疾病的遗传工具的共同兴趣的研究人员聚集在一起。基本上，所有人类疾病都是复杂的，因为发病率、严重性和结果是由许多基因和环境因素之间的相互作用决定的。癌症、糖尿病、心脏病和肺病、阿尔茨海默氏症和传染病都属于这一类。课程将包括：小鼠单倍型结构，寻找数量性状基因的策略，大脑结构和功能的基因组-QTL组合分析，检测和定位癌症修饰基因，基因-环境相互作用，系统生物学和复杂性状，分析复杂性状和复杂性状分析资源。会议还将包括海报会议和圆桌讨论会议，由大卫·斯里德吉尔主持，主题为“复杂的特质：我们如何到达终点线”。这次会议的目的是将具有不同专业知识和经验的学生和知名研究人员聚集在一起，讨论他们的研究成果，确定共同研究感兴趣的领域，并制定未来的方向。受邀的演讲者将介绍背景，提出重要的科学问题，或讨论他们自己在复杂特征分析主题领域的工作，这些领域直接影响或以其他方式将实验室小鼠用作遗传模型系统。鼓励博士后实习生和研究生参加，并提供优惠的费率和住房补贴，以鼓励他们以及妇女和任职人数不足的少数群体参加。由于其相对较小的规模和互动形式，这次会议为知名研究人员和学生提供了一个独特而难得的机会，让他们与演讲者和我们期望参加的其他专家互动。

DESCRIPTION (provided by applicant): This application is for support of the "Complex Trait Consortium 2004, 3rd Annual Conference" to be held at The Jackson Laboratory (TJL) in Bar Harbor Maine on July 6-9. The goal of the Complex Trait Consortium (CTC) meeting is to bring together investigators who have a common interest in the development and use of the laboratory mouse as a genetic tool for understanding human health and disease. Essentially all human diseases are complex in the sense that incidence, severity, and outcome are determined by interactions among many genes and environmental factors. Cancer, diabetes, heart and lung disease, Alzheimer's, and infectious diseases all fall into this category. Sessions will include: mouse haplotype structure, strategies for finding quantitative trait genes, combined genomic-QTL analysis of brain structure and function, detecting and mapping cancer modifier genes, gene-environment interactions, systems biology and complex traits, analyzing complex traits and resources for complex trait analysis. The conference will also include a poster session as well as a roundtable discussion session "Complex traits: how can we get to the finish line" to be chaired by David Threadgill. The intent of this meeting is to bring students and established investigators with varying expertise and experience together to discuss their research findings, identify areas of common research interest and develop future directions. Invited speakers will present background, raise important scientific questions or discuss their own work in topic areas of complex trait analysis that impact directly on, or otherwise use the laboratory mouse as a genetic model system. Postdoctoral trainees and graduate students are encouraged to attend, and reduced rates and housing subsidies are available to encourage their participation as well as that of women and under-represented minorities. Due to its relatively small size and interactive format, this conference represents a unique and rare opportunity for established investigators and students to interact with speakers and other experts that we expect to attend.