Complex Trait Consortium 2004, 3rd Annual Conference

描述（由申请人提供）：本申请是为了支持将于7月6日至9日在缅因州巴尔港杰克逊实验室（TJL）举行的“复杂性状联盟2004年第三届年会”。复杂性状联盟（CTC）会议的目标是将对开发和使用实验室小鼠作为了解人类健康和疾病的遗传工具有共同兴趣的研究人员聚集在一起。基本上所有人类疾病都是复杂的，因为发病率、严重程度和结果是由许多基因和环境因素之间的相互作用决定的。癌症、糖尿病、心肺疾病、老年痴呆症和传染病都属于这一类。会议将包括：小鼠单倍型结构，寻找数量性状基因的策略，脑结构和功能的基因组- qtl联合分析，癌症修饰基因的检测和定位，基因-环境相互作用，系统生物学和复杂性状，分析复杂性状和复杂性状分析资源。会议还将包括一个海报环节，以及由David Threadgill主持的圆桌讨论会“复杂特征：我们如何到达终点线”。本次会议的目的是将具有不同专业知识和经验的学生和知名研究人员聚集在一起，讨论他们的研究成果，确定共同研究兴趣的领域，并制定未来的方向。受邀演讲者将介绍背景，提出重要的科学问题或讨论他们自己在复杂性状分析主题领域的工作，这些主题直接影响或以其他方式使用实验室小鼠作为遗传模型系统。鼓励博士后培训生和研究生参加，并提供降低费率和住房补贴，以鼓励他们以及妇女和代表性不足的少数民族的参与。由于其相对较小的规模和互动形式，本次会议为已建立的研究人员和学生提供了一个独特而难得的机会，可以与我们期望参加的演讲者和其他专家进行互动。

DESCRIPTION (provided by applicant): This application is for support of the "Complex Trait Consortium 2004, 3rd Annual Conference" to be held at The Jackson Laboratory (TJL) in Bar Harbor Maine on July 6-9. The goal of the Complex Trait Consortium (CTC) meeting is to bring together investigators who have a common interest in the development and use of the laboratory mouse as a genetic tool for understanding human health and disease. Essentially all human diseases are complex in the sense that incidence, severity, and outcome are determined by interactions among many genes and environmental factors. Cancer, diabetes, heart and lung disease, Alzheimer's, and infectious diseases all fall into this category. Sessions will include: mouse haplotype structure, strategies for finding quantitative trait genes, combined genomic-QTL analysis of brain structure and function, detecting and mapping cancer modifier genes, gene-environment interactions, systems biology and complex traits, analyzing complex traits and resources for complex trait analysis. The conference will also include a poster session as well as a roundtable discussion session "Complex traits: how can we get to the finish line" to be chaired by David Threadgill. The intent of this meeting is to bring students and established investigators with varying expertise and experience together to discuss their research findings, identify areas of common research interest and develop future directions. Invited speakers will present background, raise important scientific questions or discuss their own work in topic areas of complex trait analysis that impact directly on, or otherwise use the laboratory mouse as a genetic model system. Postdoctoral trainees and graduate students are encouraged to attend, and reduced rates and housing subsidies are available to encourage their participation as well as that of women and under-represented minorities. Due to its relatively small size and interactive format, this conference represents a unique and rare opportunity for established investigators and students to interact with speakers and other experts that we expect to attend.