International Conference on Malignant Bowel Obstruction

描述（由申请人提供）：对晚期疾病患者的护理在癌症患者的连续护理中越来越重要。癌症幸存者研究的重点是被诊断患有癌症或患有癌症及其治疗的晚期或长期影响的个人的健康和生活。它还包括晚期疾病患者的需求。目前缺乏精心设计的临床研究，重点关注癌症患者的姑息治疗，特别是那些接近生命终点的患者。造成这种情况的原因有很多，包括进行此类试验的伦理困境、各专科之间的沟通障碍以及最佳护理实践标准不明确。为确保向患有不治之症的患者提供最好的护理，必须制定和传播非常适合这一人群的研究方法。鉴于生命结束体验的多维性和文化依赖性，有必要采用跨学科的方法来开发研究方法。作为启动姑息治疗临床研究方法学发展的一种手段，我们建议以恶性肠梗阻（MBO）为目标，这是一个常见的临床问题，显然需要姑息治疗研究。尽管已经提出了大量的MBO治疗方案，但现有文献在最佳管理算法方面提供的指导很少。我们建议于2004年11月12日至13日在加州帕萨迪纳召开一次由生活质量研究、民族文化差异、姑息医学、外科肿瘤学、胃肠病学、主要联合研究、医学伦理和患者倡导/癌症幸存者等国家领导人参加的跨学科峰会。选定的参与者还代表了发展对文化敏感的研究方法所需的广泛的民族和种族观点。使用MBO作为模型，将在方法学方法和姑息治疗研究的实施上达成共识。

DESCRIPTION (provided by applicant): Care for patients with terminal illness is gaining increased prominence in the continuum of care for cancer patients. Cancer survivorship research focuses on the health and life of individuals diagnosed with and living with the late or long-term effects of cancer and its treatments. It also encompasses the needs of patients with advanced disease. There is a dearth of well-designed clinical research focusing on palliative care in cancer patients and especially those who are near the end of life. There are many reasons for this, including ethical dilemmas in conducting such trials, communication barriers between specialties, and unclear standards for best care practices. To ensure that patients with incurable illnesses are offered the best available care, it is essential to develop and disseminate research methodologies well suited to this population. Given the multidimensional and culture-dependent nature of the end of life experience, it is necessary to adopt an interdisciplinary approach to developing research methods. As a means of initiating the process of palliative clinical research methodology development we propose to target malignant bowel obstruction (MBO), a common clinical problem for which palliative care research is clearly needed. Although a plethora of treatment options for MBO have been proposed, existing literature offers little guidance with regard to algorithms for optimal management. We propose to convene an interdisciplinary summit of national leaders in quality of life research, ethno-cultural variability, palliative medicine, surgical oncology, gastroenterology, major consortium research, medical ethics, and patient advocacy/cancer survivors in Pasadena, California, on November 12-13, 2004. Participants have also been selected to represent the broad ethnic and racial perspectives required to develop culturally sensitive research methods. Using MBO as a model, a consensus will be attained for methodological approaches and the implementation of palliative care research.