The Laboratory Mouse in Vision Research

描述（由申请人提供）：本申请是为了支持将于2004年10月14日至16日在缅因州巴尔港的杰克逊实验室（TJL）举行的“视觉研究中的实验室老鼠”会议。会议的功能是为使用实验室小鼠作为遗传模型系统进行眼睛研究的研究人员和学生提供一个互动论坛。实验室小鼠被广泛认为是遗传研究的首要实验生物，这些研究通常对人眼生物学和疾病有直接的影响。会议将包括：1)光感受器/转导，2)内视网膜处理和3)中央视觉系统。本次会议的目的是将具有不同专业知识和经验的学生和知名研究人员聚集在一起，讨论他们的研究成果，确定共同研究兴趣的领域，并制定未来的方向。受邀演讲者将介绍背景，提出重要的科学问题或讨论他们自己在视觉研究主题领域的工作。这些演讲之后通常会有几次15-20分钟的演讲，主要从提交的摘要中选择。将选择这些演示文稿来说明和检查概述中制定的更详细的原则。会议将有一个海报环节和9个研讨会，主题包括：1)临床评估，2)组织学评估，3)电生理学，4)基因操作，5)基因定位/修饰剂，6)小鼠突变资源，7)微阵列实验设计与分析，8)蛋白质组学和9)拨款写作。鼓励博士后和研究生参加，并为学生旅行提供资金，使学生和代表性不足的少数民族更容易参加会议。由于其相对较小的规模和互动形式，本次会议为已建立的研究人员和学生提供了一个独特而难得的机会，可以与我们期望参加的演讲者和其他专家进行互动。

DESCRIPTION (provided by applicant): This application is for support of the meeting "The Laboratory Mouse in Vision Research" to be held at The Jackson Laboratory (TJL) in Bar Harbor, Maine on October 14-16, 2004. The function of the meeting is to provide an interactive forum for investigators and students working in eye research using the laboratory mouse as a genetic model system. The laboratory mouse is widely considered the premiere experimental organism for genetic studies that have implications, often direct, for human eye biology and disease. Sessions will include: 1) Photoreceptors/transduction, 2) Inner retinal processing and 3) Central vision systems. The intent of this meeting is to bring students and established investigators with varying expertise and experience together to discuss their research findings, identify areas of common research interest and develop future directions. Invited speakers will present background, raise important scientific questions or discuss their own work in topic areas of vision research. These talks will often be followed by several presentations of 15-20 minutes each, to be chosen primarily from submitted abstracts. These presentations will be selected to illustrate and examine in more detail principles developed in the overviews. There will be one poster session and 9 workshops on topics including: 1) Clinical assessment, 2) Histological assessment, 3) Electrophysiology, 4) Genetic manipulation, 5) Genetic mapping/modifiers, 6) Mouse Mutant Resources, 7) Microarray Experiment Design and Analysis, 8) Proteomics and 9) Grant writing. Postdoctoral and graduate students are encouraged to attend, and funds for student travel will be made available to make the meeting more accessible both to students and under-represented minorities. Due to its relatively small size and interactive format, this meeting represents a unique and rare opportunity for established investigators and students to interact with speakers and other experts that we expect to attend.