To divide or not? The importance of division to hair formation in plants.

分还是不分？

• 批准号: 2444877
• 金额: --
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2444877
• 关键词: divide; importance; division; hair; formation

Multi-cellular hairs (trichomes) are important chemical factories in plants (producing flavours and fragrances) and provide them with protection against biotic and abiotic stresses. Understanding of the genetic control of multicellular hairs is limited and this project aims to build knowledge of this genetic control in tomato, using newly-produced mutants in key regulatory genes. The project aims to compare regulation of multicellular hair development in tomato with single-celled hair development in Arabidopsis and to establish how the induction of DNA replication without cell division (endoreduplication) came to be the key regulatory step in hair development in Brassica species like Arabidopsis. This project will offer state-of-the-art training in bioimaging, particularly scanning electron microscopy, genetics, synthetic biology, genome editing, cell fractionation, evolutionary biology and techniques for characterising gene function, in the context of the evolution of development in plants.

多细胞毛(毛状体)是植物中重要的化学工厂(产生香料和香料)，为它们提供抵御生物和非生物胁迫的保护。对多细胞毛发的遗传控制的了解有限，该项目旨在利用关键调控基因中新产生的突变，在番茄中建立这种遗传控制的知识。该项目旨在比较番茄和拟南芥对多细胞毛发发育的调控，并确定诱导DNA复制而不进行细胞分裂(内复制)是如何成为拟南芥等油菜种毛发发育的关键调控步骤。该项目将提供最先进的生物成像培训，特别是在植物发育进化的背景下，扫描电子显微镜、遗传学、合成生物学、基因组编辑、细胞分离、进化生物学和表征基因功能的技术。