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Diet, Colon Cancer, and Cancer Communications

饮食、结肠癌和癌症通讯

基本信息

批准号：
6771747
负责人：
JESSIE A SATIA (Deceased)
金额：
$ 15.35万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2002
资助国家：
美国
起止时间：
2002-09-10 至 2008-07-31
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): This application describes a career development/transition plan for Jessie A. Satia, PhD, MPH, a newly appointed Assistant Professor in the Department of Nutrition at the University of North Carolina, Chapel Hill. The candidate's overall career goal is to establish an interdisciplinary research career combining her background in epidemiology, nutrition, and laboratory sciences to conduct methodologic, observational, and intervention studies of diet and human cancers. In particular, she would like to conduct studies to identify risk factors for cancer and design appropriate interventions for prevention and control in minority and underserved populations. The candidate proposes a career development plan that includes: teaching and mentoring students; submitting research manuscripts and pilot project proposals; and a research plan (75% of her effort) with two proposed projects. Project 1 titled "Cancer Communications among African American Adolescents" aims to collect information necessary to design diet-related cancer prevention messages for African American adolescents; and evaluate the effectiveness of messages framed in different ways on knowledge, attitudes, beliefs, and intentions to improve diet in this population. Qualitative methods will be used to collect information on various factors that affect dietary behavior among African American adolescents (14 to 16 years) in Durham, NC. This information will then be used to design messages focused on lowering dietary fat intake in this population that will be delivered via the Internet. Participants will be randomized into four groups based on Prospect theory and message framing, and will complete pre- and post-tests and cognitive interviews to assess the short-term impact of the framed messages. Project 2, "Diet and Colon Cancer in African Americans and Whites in North Carolina" describes proposed analyses using previously collected data from a study of 654 colon cancer cases (40-80 years) and 1067 population-based controls, with equal numbers of African Americans and whites, in a 33-county area of North Carolina. The specific aims of the analyses proposed here are to examine effects of dietary factors (e.g., fat, fruits, vegetables, antioxidants, fiber, alcohol, and total calories) and food intake patterns (meal frequency and snacking timing) on colon cancer risk. Potential future research opportunities using biological specimens from this study are described. The long-term success of cancer research efforts rests, in part, on building the career of talented young faculty. Obtaining this award will greatly broaden and strengthen the candidate's focus on cancer prevention and control.

描述（由申请人提供）：本申请描述了杰西A的职业发展/过渡计划。Satia博士，公共卫生硕士，查佩尔山北卡罗来纳州大学营养系新任命的助理教授。候选人的总体职业目标是建立一个跨学科的研究生涯，结合她在流行病学，营养学和实验室科学的背景，进行饮食和人类癌症的方法学，观察和干预研究。特别是，她希望开展研究，以确定癌症的风险因素，并设计适当的干预措施，以预防和控制少数群体和得不到充分服务的人口。候选人提出了一个职业发展计划，其中包括：教学和指导学生;提交研究手稿和试点项目提案;和研究计划（她的努力的75%）与两个拟议的项目。项目1名为“非裔美国青少年癌症交流”，旨在收集必要的信息，为非裔美国青少年设计与饮食有关的癌症预防信息;并评估以不同方式构建的信息的有效性，包括知识，态度，信仰和意图，以改善这一人群的饮食。将采用定性方法收集影响北卡罗来纳州达勒姆非裔美国青少年（14至16岁）饮食行为的各种因素的信息。然后，这些信息将用于设计通过互联网传递的信息，重点是降低这一人群的膳食脂肪摄入量。参与者将根据前景理论和信息框架被随机分为四组，并将完成前后测试和认知访谈，以评估框架信息的短期影响。项目2“北卡罗来纳州非裔美国人和白人的饮食与结肠癌”描述了使用先前从北卡罗来纳州33个县的654例结肠癌病例（40-80岁）和1067例基于人群的对照研究中收集的数据进行的拟议分析，其中非裔美国人和白人的数量相等。这里提出的分析的具体目的是检查饮食因素的影响（例如，脂肪、水果、蔬菜、抗氧化剂、纤维、酒精和总热量）和食物摄入模式（用餐频率和吃零食的时间）对结肠癌风险的影响。潜在的未来的研究机会，从这项研究中使用的生物标本。癌症研究工作的长期成功部分取决于有才华的年轻教师的职业生涯。获得该奖项将大大拓宽和加强候选人对癌症预防和控制的关注。