Outcomes of Preschool Mental Health Problems

学前心理健康问题的后果

• 批准号: 6989592
• 负责人: ADRIAN C ANGOLD
• 金额: $ 60.32万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-23 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6989592
• 关键词: anxiety; anxiety disorders; behavior prediction; behavior test; behavioral /social science research tag; child mental disorders; child psychology; clinical depression; clinical research; comorbidity; depression; disease /disorder proneness /risk; functional ability; human subject; longitudinal human study; mental disorder diagnosis; mental health epidemiology; neuropsychological tests; parent offspring interaction; pathologic process; patient oriented research; preschool child (1-5); prognosis; psychopathology; sign /symptom; social behavior

DESCRIPTION (provided by applicant): The aim of this application, "Outcomes of Preschool Mental Health Problems," is to examine the predictive validity of preschool anxiety and depressive symptoms, syndromes, and disorders that present in the preschool period at follow-up 3 1/2 to 6 1/2 years after the initial psychiatric assessment. We propose to build upon a study of 307 children aged 2 to 5 involved in a successful test-retest study of a psychiatric diagnostic interview for parents of preschoolers (the Preschool Age Psychiatric Assessment- PAPA). In the original study, we screened 1,073 parents of preschool children attending a general pediatric clinic with the parent report Child Behavior Checklist 11/2-5 (CBCL). Parents of children screening at or above the 30th percentile (N=193) and a random selection of the rest (N=114) were administered the PAPA twice separated by a week. The sample was stratified by age (2-5), gender, and race (African-American versus non-African-American). Data can be weighted back to the screening population. Here we propose to add 3 waves of follow-ups to this study, the first a 3 1/2 year follow-up, with 2 subsequent 18 month follow-ups. Across these 3 waves, the children's ages will range from 5 1/2 to 11 1/2 years old. We will use multi-modal, multi-informant assessments of psychiatric symptoms and disorders, as well as measures of developmental status, parent-child interactions, and risk factors known to be associated with psychiatric symptoms in older children.} Predictive validity will be examined through (1) temporal stability of psychiatric symptoms, syndromes, and disorders and (2) prediction of preschool symptoms to later psychiatric symptoms, disorders, and impairment and (3) association of early childhood anxiety and depressive symptoms and disorders with psychosocial impairment, neurocognitive deficits, particularly language problems, and risk factors including adverse life events, problems in the parent-child relationship, parental stress, and parental psychopathology. In the absence of any gold-standard for the identification of preschool psychiatric syndromes we adopt a construct-validation approach based on reasonable expectations for (1) stability over time of (a) syndrome scale scores (e.g., count of depressive symptoms) and (b) categorical syndromes (e.g., major depressive disorder) (homotypic continuity); (2) continuity of syndrome scale score and categorical syndrome problems even when those problems change in form over time (e.g., from depressive to conduct symptoms - heterotypie continuity).

描述（由申请人提供）：本申请的目的是“学龄前心理健康问题的结果”，是为了检查学龄前焦虑和抑郁症状，综合症和疾病的预测有效性，这些疾病是在最初的心理评估后3 1/2至6 1/2年中的幼儿园期间存在的。我们建议对307名2至5岁儿童的研究进行研究，该研究是对学龄前儿童的父母进行精神诊断访谈的成功测试研究（学龄前年龄的精神病学评估-PAPA）。在最初的研究中，我们筛选了1,073名学龄前儿童的父母，该儿童参加了一家普通儿科诊所，父母报告儿童行为清单11/2-5（CBCL）。在第30个百分位数（n = 193）中进行筛查的孩子的父母和其余的随机选择（n = 114）被两次分隔一周。样本按年龄（2-5），性别和种族（非裔美国人与非非洲裔美国人）分层。数据可以加权回到筛选人群。在这里，我们建议在这项研究中添加3浪随访，这是第一个3 1/2年的随访，随后有2个随后的18个月随访。在这3浪中，儿童的年龄将在5 1/2到11 1/2岁之间。我们将使用对精神症状和疾病的多模式，多信息评估，以及发育状况，亲子互动的措施，父子互动和已知与年龄较大儿童精神症状相关的风险因素。}预测有效性。症状，疾病和障碍以及（3）幼儿焦虑，抑郁症状和疾病与心理社会障碍，神经认知能力缺陷，尤其是语言问题，包括不良生活事件，父母关系中的问题，父母压力，父母压力和父母心理病理在内的危险因素的关联。在没有任何金色标准的情况下，我们基于对（1）对（1）（1）稳定性稳定的综合量表得分（例如抑郁症状计数）和（b）分类综合症（例如，抑郁症的综合症（例如，主要的抑郁症）（主要的抑郁症）（Homerotsypics Reltistice duities）（抑郁症状计数）（例如，抑郁症状计数）（例如，抑郁症状计数）（例如，抑郁症状计数）（例如，抑郁症状计数）（例如，抑郁症状计数）（例如，抑郁症状计数）; （2）即使这些问题随时间变化（例如，从抑郁到进行症状 - 异型连续性），综合征量表评分和分类综合征问题的连续性即使。