Incorporating Chiral Cations into Transition Metal Catalysis

将手性阳离子纳入过渡金属催化

• 批准号: 2459173
• 金额: --
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2459173
• 关键词: Incorporating; Chiral; Cations; into; Transition

Chiral cations have been used extensively as organocatalysts but it is very rare for them to be used as chiral controller for versatile and reactive transition metals, despite the obvious potential. This project uses anionic ligands to incorporate chiral cations into various mainstream transition metal catalysed processes that are difficult to render chiral through conventional means. We plan to investigate a range of processes and assess the broader viability of this strategy.

手性阳离子作为有机催化剂已被广泛应用，但作为多功能活性过渡金属的手性控制剂却非常少见，尽管它们具有明显的潜力。该项目使用阴离子配体将手性阳离子引入到各种主流的过渡金属催化过程中，这些过程难以通过常规手段呈现手性。我们计划调查一系列过程，并评估这一战略的更广泛可行性。