Exploring roles for microRNAs in cancer using bioinformatics and gene expression tools.

微rna是一种新发现的化学物质，是2006年诺贝尔医学奖的主题。这些化学物质减少了细胞中特定分子“目标”的数量，并在癌症中发挥重要作用。目前我们还不知道这些化学物质是如何选择它们的目标的，我们建议使用基于计算机的方法来发现它们是如何影响癌症基因的。这将提高我们对癌症的了解，从而导致新的抗癌疗法的发现。

microRNAs are newly discovered chemicals that were the subject of the 2006 Nobel Prize in Medicine. These chemicals decrease the amount of specific molecular ‘targets’ in cells, and play an important role in cancer. Currently we do not understand how these chemicals choose their targets, and we propose to use a computer-based approach to discover how they affect genes in cancer. This will improve our understanding of cancer and thereby lead to the discovery of novel anti-cancer therapies.