Neuroscience: From Channels to Behavior

描述（由申请人提供）：这是一个在布兰代斯大学神经科学博士前培训计划继续资助的请求。我们的计划是在Volen复杂系统中心的保护伞下组织的，由神经科学计划主席John Lisman领导。我们建议每年培养11名在分子，细胞，系统，认知和计算神经科学领域的博士生。培训教师包括生物学，生物化学，化学，心理学和物理学系的22名成员。现有的研究项目从神经元的基本分子和细胞研究到失语症和癫痫等神经系统疾病的临床患者的研究。具体的主题包括离子通道的生物物理学，信号转导，神经遗传学，昼夜节律，发育神经生物学，神经振荡的电路动力学，学习和记忆以及运动控制。学员是从我们的神经科学研究生的大池选择。他们将满足神经科学博士课程的所有实验室轮换要求，课程和资格考试要求，将在培训教师之一的实验室进行博士论文研究，并将参加包括我们的神经生物学杂志俱乐部和系列讲座在内的培训活动。此外，他们将每年向神经科学界介绍他们的研究进展。所有受训人员都将参加负责任的科学行为课程。我们广泛的培训环境和计算神经科学的优势为教授学生如何从分子，细胞和网络过程中产生认知相关的大脑计算提供了独特的环境。

DESCRIPTION (provided by applicant): This is a request for continued funding of the predoctoral training program in Neuroscience at Brandeis University. Our program is organized under the umbrella of the Volen Center for Complex Systems and is headed by John Lisman, chairperson of the Neuroscience Program. We propose to train 11 predoctoral students per year in the fields of molecular, cellular, systems, cognitive, and computational neuroscience. The training faculty includes 22 members of the Biology, Biochemistry, Chemistry, Psychology and Physics Departments. Available research projects run the full range from basic molecular and cellular studies of neurons to research with clinical patients with neurological disorders such as aphasia and epilepsy. Specific topics include the biophysics of ion channels, signal transduction, neurogenetics, circadian rhythms, developmental neurobiology, the circuit dynamics of neural oscillations, learning and memory and motor control. Trainees are chosen from our large pool of neuroscience graduate students. They will satisfy all the laboratory rotation requirements, course and qualifying exam requirements of the neuroscience PhD program, will carry out PhD thesis research in the laboratory of one of the training faculty and will participate in training activities that include our Neurobiology Journal club and lecture series. In addition, they will make an annual presentation of their research progress to the Neuroscience community. All trainees will attend and participate in a course in the responsible conduct of science. Our broad-based training environment and strengths in computational neuroscience provide a unique environment for teaching students how cognitively relevant brain computations emerge from molecular, cellular and network processes.