TRAINING PROGRAM IN ORGANOGENESIS

器官发生培训计划

• 批准号: 6891709
• 负责人: DEBORAH L. GUMUCIO
• 金额: $ 26.72万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-14 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6891709
• 关键词: TRAINING; PROGRAM; ORGANOGENESIS

DESCRIPTION (provided by applicant): The field of organogenesis unites clinical, basic science and applied researchers with a common goal: To understand the basic mechanisms by which organs and tissues are formed and maintained, and to use this knowledge to create long lasting artificial organs, stem cell therapies or organ transplantation systems that will correct genetic and acquired diseases. As such, the field of organogenesis requires an interdisciplinary approach in which information and ideas can be readily shared among scientists with a broad range of backgrounds and expertise. This facile exchange will speed the rate at which important findings in basic research are translated therapeutic advances while simultaneously fostering constant improvements in the available in vitro models for the study of organ development, function and disease. Through the Center for Organogenesis, the University of Michigan is actively coalescing strengths in the area of organogenesis. The Organogenesis Training Program described in this application is an outgrowth of those efforts and is designed to meet two objectives: a) to provide trainees with intellectual and technical training in the field of organogenesis and b) to encourage and enhance the ability of trainees to cross interdisciplinary boundaries within this field. The first objective is accomplished by requiring all trainees to participate in several specific training activities, including formal courses in Organogenesis, a Monthly Seminar Series, a Monthly Trainee Meeting and the Organogenesis Students and Fellows Association (OSFA). The "Organogenesis of Complex Tissues" course, which is centered on three specific organs per term, is structured to expose students to information, techniques and schools of thought that comprise the field of organogenesis as defined above. OSFA is an already active group sponsored by the Center for Organogenesis and is composed of graduate students and postdoctoral fellows who are involved or are interested in organogenesis research. To meet the second objective of the training program, a two mentor training structure is required of all trainees. The primary mentor will be one of the 32 investigators listed in this application. A secondary mentor will be chosen by the trainee and primary mentor as an investigator who can provide an approach, technique or viewpoint not already available to the trainee. Formal applications for support will be required from all prospective trainees and will be reviewed by an interdisciplinary Operating Committee. This proposal requests support for 6 predoctoral and 4 postdoctoral trainees (three with Ph.D. degrees and one with M.D. or M.D,/Ph.D. degrees) per year.

描述（由申请人提供）：器官发生领域 临床，基础科学和应用研究人员有一个共同的目标： 了解器官和组织形成的基本机制， 保持，并利用这些知识来创造持久的人工 器官、干细胞疗法或器官移植系统， 遗传和获得性疾病。因此，器官发生领域需要 跨学科的方法，信息和想法可以很容易地 在具有广泛背景和专业知识的科学家之间共享。这 简单的交流将加快基本研究中重要发现的速度。 研究转化为治疗进展，同时促进 不断改进用于研究器官的体外模型， 发育、功能和疾病。通过器官发生中心， 密歇根大学正在积极整合该领域的优势， 器官发生器官发生训练计划描述在这 应用程序是这些努力的产物，旨在满足两个 目标：a）为学员提供知识和技术培训， 器官发生领域和B）鼓励和提高 学员在这个领域跨越跨学科的界限。第一 为实现这一目标，要求所有受训人员参加几个 具体的培训活动，包括器官形成方面的正式课程，a 每月研讨会系列，每月实习生会议和器官发生 学生和研究员协会（OSFA）。复合体的器官发生 组织”课程，每学期以三个特定器官为中心， 结构，让学生接触到信息，技术和学校， 认为其包括如上文所定义的器官发生领域。OSFA是一个 由器官发生中心赞助的一个已经很活跃的组织， 的研究生和博士后研究员谁参与或正在 对器官形成研究感兴趣为了实现《公约》的第二个目标， 培训计划，要求所有受训者都有两个导师的培训结构。 主要导师将是本报告中列出的32名研究者之一。 应用程序.第二导师将由受训者和主要导师选择。 导师作为研究者，可以提供方法、技术或观点 还没有提供给学员。正式的支持申请将 要求所有潜在的学员，并将审查 跨学科运营委员会该提案要求支持6 博士前和4名博士后（3名拥有博士学位）度和一个与 M.D.或医学博士或哲学博士度）。