GRADUATE TRAINING IN SYSTEMS AND INTEGRATIVE PHYSIOLOGY

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EXCEED THE SPACE PROVIDED. The Systems and Integrative Physiology Training Program continues to provide individuals at the pre-doctoral level with the scientific background and research experience in the area of systems and integrative physiology that will enable participants to pursue careers in physiological research. Funding is again requested for eight pre-doctoral trainee positions. Training is based on ourinterdisciplinary Graduate Program in Physiological Sciences with intensive research opportunities in the general areas of cardiovascular biology, cell physiology, applied physiology, neurobiology, endocrinology and reproductive physiology, and renal and transport physiology. Within these general areas the 26 training faculty are engaged in specific research in function and integration of the cardiovascular, endocrine, gastrointestinal, muscular, neural, renal and respiratory systems. Studies range form wholly experimental to purely theoretical. The faculty are notable for their high level of research activity (allhave one or more extramural research grants) extensive formal and informal interactions, and close working relationships between the current 12 participating departments. Each faculty member is strongly committed to the goal of interdisciplinary training in systems and integrative physiology. Our trainees are offered an exceptional opportunity to specialize while obtaining a general interdisciplinary background in systems and integrative physiology. Predoctoral training requires approximately five years. The first year is built around a course sequence in cellular/molecular and systems physiology, complemented by laboratory rotations, colloquia, and tutorials designed to provide a broad background in the discipline and introduce the trainee to research laboratories early in their training. Trainees also attend and present in the Program's "Student Forum" seminar series which is put together and run solely by students in the Physiological Sciences Program. They also obtain training regarding ethics and conduct in science. During the second year, the trainees take coursework more narrowly focused on their area of specialization and continue with laboratory rotations. During this period, a dissertation director is selected along with a committee and the student takes a comprehensive exam. Upon completion of the comprehensive exam, a written research proposal is begun. Third and subsequent years are largely devoted to research complemented by participation in a year-round seminar series. Predoctoral trainees must have a B.S.-or B.A. in the biological, physical or engineering sciences. They are admitted to the Graduate Program in Physiological Sciences which is interdisciplinary in nature and comprised of faculty from 5 Colleges, 18 departments and one institute, and joint appointees between the UA and our other Arizona Universities. Recruits are selected on the basis of academic performance, prior research experiences and motivation toward a research career in physiology. These qualities are assessed from grades, GRE scores, letters of recommendation and personal interviews. Trainees to be supported by this training grant will be selected based on their research interests as related to systems and integrative physiology, and mentor selection. PERFORMANCE SITE ========================================Section End===========================================