12th International Symposium on Basement Membranes

描述（由申请人提供）：提交此R13申请是为了请求对将于2005年6月15日至18日在宾夕法尼亚州费城杰斐逊医学院举行的第12届基底膜国际研讨会（ISBM）的部分支持。地下室膜国际研讨会是一系列两年一次的活动，在欧洲、日本和美国的地点轮流举行。本申请的主要研究者Jouni Uitto博士在2003年于日本举行的前一次会议上当选为本次研讨会的主席。研讨会副主席朱孟立博士和代表皮肤科和皮肤生物学系的当地组织委员会;病理学，解剖学和细胞生物学;医学/流变学和血液学;矫形研究;和遗传学;以及杰斐逊医学院院长办公室协助组织这次会议。当地组织委员会得到一个著名的国际咨询委员会的协助。 本次研讨会的主要目标是为在基底膜生物学和病理学广泛领域工作的主要科学家提供一个国际论坛，与人类疾病有关。第12届国际弹道导弹会议将围绕以下主题举行四个专题会议：1.基底膜的组装和结构-功能关系：2。基底膜发育与干细胞生物学; 3.基底膜生物学作用的遗传学方法：和4。基底膜疾病的分子基础。这些会议共有12位特邀演讲者，他们是根据其科学卓越性和公认的与广大听众沟通的能力而被选中的。此外，将从提交海报展示的摘要中选出18个简短的平台展示，主要由年轻和新的实地研究人员提供。观众，预计将包括200-250名参与者，包括广泛的既定生物化学家，结构和分子生物学家，医生科学家和临床医生。此外，我们预计该领域的大量年轻和新的研究人员-学生，博士后研究员和居民-将参与其中。我们认为，本次会议非常及时，预计将证明其在为未来的研究团队带来跨学科方法方面的有用性，以及加强基础科学向临床实践的转化。从这个意义上说，这次会议将实现美国国立卫生研究院路线图倡议的一些目标。

DESCRIPTION (provided by applicant): This R13 application is submitted to request partial support for The 12th International Symposium on Basement Membranes (ISBM), to be held at Jefferson Medical College, Philadelphia, Pennsylvania, June 15-18, 2005. The International Symposia on Basement Membranes is a series of biennial events that rotate between sites in Europe, Japan and the United States. The Principal Investigator of this application, Dr. Jouni Uitto, was elected as the President of this Symposium in the prior meeting held in Japan, 2003. He is assisted in organizing this meeting by Dr. Mon-Li Chu, Vice President of the Symposium, and by the Local Organizing Committee representing Departments of Dermatology and Cutaneous Biology; Pathology, Anatomy and Cell Biology; Medicine/Rheumatology and Hematology; Orthopaedic Research; and Genetics; as well as the Office of the Dean of Jefferson Medical College. The Local Organizing Committee is assisted by a distinguished International Advisory Board. The principal objective of this Symposium is to provide an international forum for the cadre of premier scientists working in the broad fields of basement membrane biology and pathology, with relevance to human diseases. The 12th ISBM will consist of four thematic sessions revolving around the following topics: 1. Assembly and Structure-Function Relationships of Basement Membranes: 2. Basement Membrane Development and Stem Cell Biology; 3. Genetic Approaches to the Biological Role of Basement Membranes: and 4. Molecular Basis of Diseases of Basement Membrane. These sessions feature a total of 12 invited speakers who have been selected on the basis of their scientific excellence and recognized ability to communicate with a broad audience. In addition, 18 short platform presentations, given primarily by young and new investigators to the field, will be selected from abstracts submitted for poster presentation. The audience, expected to consist of 200-250 participants, comprises a broad spectrum of established biochemists, structural and molecular biologists, physician-scientists and clinicians. In addition, we expect a significant number of young and new investigators in the field - students, postdoctoral fellows, and residents - to participate. We believe that the current meeting is extremely timely, and it is expected to prove its usefulness in bringing interdisciplinary approaches for the research teams of the future, as well as to enhance the translation of basic sciences to the clinical practice. In that sense, the meeting will meet some of the goals of the National Institutes of Health Roadmap Initiative.