Understanding cell division in industrial and medical important bacteria

了解工业和医学重要细菌的细胞分裂

• 批准号: 2584944
• 金额: --
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2584944
• 关键词: Understanding; cell; division; industrial; medical

Every cell must divide to grow and propagate. Thus, a better understanding of this process can help in the development of new experimental strategies to prevent cell division and the spreading of disease-causing bacteria. We have recently identified a novel component of the bacterial cell division machinery that is present in many medical and industrial important bacteria, including the antibiotic producers Streptomyces and the TB-causing agent Mycobacteria tuberculosis.The aim of this project is to functionally and structurally characterise a novel cell division protein in Mycobacteria using the non-pathogenetic and fast-growing Mycobacteria smegmatis as a model system.

每个细胞都必须分裂才能生长和繁殖。因此，更好地了解这一过程有助于开发新的实验策略，以防止细胞分裂和致病细菌的传播。我们最近发现了细菌细胞分裂机制的一种新成分，存在于许多医学和工业重要细菌中，包括抗生素生产者链霉菌和结核分枝杆菌。该项目的目的是使用非致病性和快速生长的耻垢分枝杆菌作为模型，从功能和结构上表征分枝杆菌中的一种新型细胞分裂蛋白 系统。