CANCER CELL BIOLOGY TRAINING PROGRAM

超出所提供的空间。本建议是为继续在查佩尔山的北卡罗来纳州大学（UNC-CH）为博士前学生提供跨学科的癌细胞生物学培训计划。该计划的前提是UNC-CH毕业的博士生在分子和细胞生物学的范式方面受到良好的训练，但这些学生很少接受癌症病理生物学和治疗方面的重要培训。随着越来越重视转化，疾病为导向的研究，需要解决这一不足，在研究生培养已成为更紧迫的。因此，该计划的广泛目标是提供癌症生物学的全面培训，使学生能够有效地为新一轮的转化研究做出贡献。该计划非常重视癌症的组织病理学和学员接触对肿瘤生物学至关重要的主题，包括血管生成，侵袭性，转移，癌症化疗和癌症药物发现。因此，它促进了博士候选人的培训，这些博士候选人经过独特的培训，并与UNC-CH的NIH资助的各个部门或其他培训项目明确区分开来。该计划由UNC-CH的卓越教师以及完善的Lineberger综合癌症中心（LCCC）提供的领导和计划补充。39名教师导师来自10个不同的UNC-CH部门和三个跨学科的博士前培训课程。项目指导员也是LCCC的成员。该培训计划的一个关键组成部分是建立癌细胞生物学课程，其中包括专门为计划学员开发的课程，这些课程涉及癌症病理学，诊断，药物发现和治疗中的关键问题。这个博士前课程是由已经为LCCC的长期博士后培训计划开发的计划的有力补充。因此，这两个培训项目共同促进了LCCC的目标，即创造一个全面、跨学科、有凝聚力和协作的研究环境，以促进博士前和博士后癌症研究人员的发展。性能现场=

EXCEED THE SPACE PROVIDED. This proposal is for continuation of an interdisciplinary Cancer Cell Biology Training Program for predoctoral ludents at the University of North Carolina at Chapel Hill (UNC-CH). The premise of this program is that the doctoral students graduated by UNC-CH are well trained in the paradigms of molecular and cellular biology, but rarely do these students receive significant training in the pathobiology and treatment of cancer. With an ncreasing emphasis on translational, disease-oriented research, the need to address this deficiency in graduate student training has become of greater urgency. Thus, the broad goal of this program is to provide comprehensive training in cancer biology to allow students to effectively contribute to the new wave of translational research. The program provides a strong emphasis on the histopathology of cancer and the exposure of trainees to topics crucial to tumor biology, including angiogenesis, invasiveness, metastasis, cancer chemotherapy, and cancer drug discovery. Therefore, it fosters the training of doctoral candidates that are uniquely trained and clearly distinguished from those of individual departments or other training programs funded by the NIH at UNC-CH. This program is complemented by the excellence of the faculty at UNC-CH and the leadership and programs provided by the well-established Lineberger Comprehensive Cancer Center (LCCC). The 39 faculty preceptors are drawn from 10 different UNC-CH departments and three interdisciplinary predoctoral training curricula. Program preceptors are also members of the LCCC. A critical component of this training program is the establishment of a Cancer Cell Biology Curriculum that includes coursework developed specifically for the Program trainees that address key issues in cancer pathology, diagnosis, drug discovery and treatment. This predoctoral program is strongly complemented by the programs that have been developed for the LCCC's long-standing postdoctoral training program. Thus, together, these two training programs facilitate the LCCC's goal to create a comprehensive, interdisciplinary, cohesive and collaborative research environment to foster the development of both pre- and postdoctoral cancer researchers. PERFORMANCE SITE ========================================Section End===========================================