Pathobiology of Digestive Diseases

消化系统疾病病理学

• 批准号: 6897191
• 负责人: LAURA LISCUM
• 金额: $ 41.88万
• 依托单位: TUFTS UNIVERSITY BOSTON
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6897191
• 关键词: Pathobiology; Digestive; Diseases

EXCEED THE SPACE PROVIDED. A uniqueprogram is proposed to train pre- and postdoctoral PhD fellows for research careers in the pathobiology, particularly involvingdigestive diseases, and to provide physicians within-depth interdisciplinary training in modem biology as related to digestive disease pathobiology. Physicians spend three years in individualized research training, courses and laboratory rotations related to specific interests under supervision of an advisory committee. Training is supervised by 19 experienced preceptors associated with the Departments of Physiology-Pathophysiology, Medicine, Microbiology and GRASP (NIDDK - Center) at Tufts UniversitySchool of Medicine. Faculty are basic scientists and basically-oriented physician scientists who share enthusiasm for the proposed novel program and who have substantialresearch records and support in areas related to digestive diseases. The major research goal is to understandhow events on the surface of cells (i.e., pumps,channels, receptors, etc.) control gene expression as related to signal transduction, regeneration, differentiation and polarity under physiologic conditionsand in disease states. The program includesseminars, journal club and graduate courses includinga unique program in Pathobiology for PhD Students and Fellows. Our goal is to bridge the gap between major advances in biology and their application to human digestive diseases. We seek to train PhD graduates and physicianswho will work independentlywith clinicalinvestigators rather thanfor them. The major goal is to reduce the intellectual barriers which separate basic scientists from their clinical colleagues and thereby enhance the transfer of knowledge from one discipline to another. PERFORMANCE SITE ========================================Section End===========================================

超出所提供的空间。 一个独特的计划，提出了培养前和博士后博士研究员的研究生涯中的病理生物学，特别是涉及消化系统疾病，并提供医生在深入的跨学科培训，在现代生物学有关的消化系统疾病病理生物学。医生在咨询委员会的监督下，花三年时间进行与特定兴趣相关的个性化研究培训，课程和实验室轮换。培训由塔夫茨大学医学院生理-病理生理学、医学、微生物学和GRASP（NIDDK -中心）的19名经验丰富的导师监督。教师是基础科学家和基本导向的医生科学家，他们对拟议的新计划充满热情，并在消化系统疾病相关领域拥有大量的研究记录和支持。主要的研究目标是了解细胞表面的事件（即，泵、通道、受体等）在生理条件下和疾病状态下控制与信号传导、再生、分化和极性相关的基因表达。该计划包括研讨会，期刊俱乐部和研究生课程，包括一个独特的博士生和研究员病理学计划。我们的目标是弥合生物学的重大进展与其在人类消化系统疾病中的应用之间的差距。我们致力于培养博士毕业生和医生，他们将独立地与临床研究人员合作，而不是为他们工作。主要目标是减少将基础科学家与临床同事分开的知识障碍，从而促进知识从一个学科到另一个学科的转移。性能现场=