Development of a bioelectronic wound dressing to aid chronic ulcer wound repair

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The incidence of chronic wounds are increasing due to a growing and ageing population. Patients who are more susceptible to chronic ulcers include the elderly and diabetics. Over £2billion was spent on wound care in 2014 alone. Advanced wound care products are needed on chronic wounds as without intervention approximately 50% of these wounds do not heal.The role of electrical regimes in skin has been documented, with local ionic currents playing a part in directing epidermal cell migration when closing full thickness wounds.It has been recently documented that externally applied electrical stimulus can influence cell activity, both increasing cell proliferation and increasing differentiation and extracellular matrix production. This project will investigate the development of a fibrous conductive polymer wound dressing with a capacitive applied electrical field, that has the potential to aid the healing of chronic ulcers.