JOHNS HOPKINS CENTER FOR AIDS RESEARCH

约翰霍普金斯大学艾滋病研究中心

• 批准号: 7119820
• 负责人: JOHN G BARTLETT
• 金额: $ 61.7万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-29 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7119820
• 关键词: AIDS; biomedical facility

DESCRIPTION (Adapted from application): This application proposes to re-establish a CFAR at Johns Hopkins University (JHU), with the goal of fostering collaborative and innovative AIDS research at JHU. To this end, the proposed CFAR will support collection of clinical specimens from a well-characterized patient population (Clinical Core); a pilot project program that would increase the ability of productive investigators to pursue high-risk, high impact ideas (Developmental Core); key service Core facilities (Flow Cytometry and Cell Sorting Core, Monoclonal Antibody Core); and centralized administrative operations designed to disseminate key scientific information and increase intellectually fruitful contact among AIDS researchers (Administrative Core). The Administrative Core will include representatives of all disciplines of HIV/AIDS research at JHU and will regularly review the cost-effectiveness of all CFAR-supported activities, as compared to other Cores and programs that the CFAR could support. Initially, four critical aspects of HIV infection will be emphasized: 1) pathogenesis, 2) latent HIV infection, 3) immune restoration, and 4) prevention. Overall, the specific aims of the CFAR will be to disseminate scientific information among investigators, foster innovative and collaborative research, bring new investigators into HIV/AIDS research, and increase the profile of HIV/AIDS research at Johns Hopkins University.

描述（改编自应用程序）： 本申请提出 在约翰霍普金斯大学（JHU）重新建立CFAR， 在JHU促进合作和创新的艾滋病研究的目标。本 最后，拟议的CFAR将支持从 特征明确的患者人群（临床核心）;试点项目计划 这将提高富有成效的调查人员的能力， 高风险，高影响力的想法（发展核心）;关键服务核心设施 (Flow细胞计数和细胞分选核心，单克隆抗体核心）;和 旨在传播关键科学知识的集中管理业务， 信息 并增加 智力 富有成效的接触 在艾滋病中 研究人员（行政核心）。 行政核心将包括 在JHU的艾滋病毒/艾滋病研究的所有学科的代表，并将 定期审查所有CFAR支持的活动的成本效益， 与CFAR可以支持的其他核心和计划相比。 起初， 将强调艾滋病毒感染的四个关键方面：1）发病机制，2） 潜伏HIV感染，3）免疫恢复，4）预防。 总体看 CFAR的具体目标将是在以下人员中传播科学信息： 研究人员，培养创新和 合作研究，带来新的 艾滋病毒/艾滋病研究的调查人员，并提高艾滋病毒/艾滋病的形象 约翰霍普金斯大学的研究。

项目成果

Body shape and metabolic abnormalities in Thai HIV-infected patients.

泰国艾滋病毒感染者的体型和代谢异常。

• DOI: 10.1089/aid.2007.0013
• 发表时间: 2007
• 期刊: AIDS research and human retroviruses
• 影响因子: 1.5
• 作者: Homsanit,Mayuree;Nelson,KenradE;Sonjai,Areeuea;Anekthananon,Thanomsak;Suwanagool,Surapol;CofrancescoJr,Joseph
• 通讯作者: CofrancescoJr,Joseph

Distribution of cell-free and cell-associated HIV surrogates in the colon after simulated receptive anal intercourse in men who have sex with men.

• DOI: 10.1097/qai.0b013e3182373b5e
• 发表时间: 2012-01-01
• 期刊: Journal of acquired immune deficiency syndromes (1999)
• 作者: Louissaint NA;Nimmagadda S;Fuchs EJ;Bakshi RP;Cao YJ;Lee LA;Goldsmith J;Caffo BS;Du Y;King KE;Menendez FA;Torbenson MS;Hendrix CW
• 通讯作者: Hendrix CW

Knowledge, perceived stigma, and care-seeking experiences for sexually transmitted infections: a qualitative study from the perspective of public clinic attendees in Rio de Janeiro, Brazil.

从巴西里约热内卢的公共诊所与会者的角度来看，知识，感知到的性传播感染的污名和寻求护理的经历：定性研究。

• DOI: 10.1186/1471-2458-7-18
• 发表时间: 2007-02-01
• 期刊: BMC PUBLIC HEALTH
• 影响因子: 4.5
• 作者: Malta, Monica;Bastos, Francisco I.;Strathdee, Steffanie A.;Cunnigham, Shayna D.;Pilotto, Jose Henrique;Kerrigan, Deanna
• 通讯作者: Kerrigan, Deanna

RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation.

RNA结合蛋白RBM14通过调节DNA修复和细胞分化来促进胶质母细胞瘤的放射性。

• DOI: 10.18632/oncotarget.1924
• 发表时间: 2014-05-15
• 期刊: Oncotarget
• 作者: Yuan M;Eberhart CG;Kai M
• 通讯作者: Kai M

HIV-1 evolution following transmission to an HLA-B*5801-positive patient.

HIV-1 传播给 HLA-B*5801 阳性患者后的演变。

• DOI: 10.1086/648377
• 发表时间: 2009
• 期刊: The Journal of infectious diseases
• 作者: O'Connell,KarenA;Xu,Jie;Durbin,AnnaP;Apuzzo,LindaG;Imteyaz,Hejab;Williams,ThomasM;Ray,StuartC;Margolick,JosephB;Siliciano,RobertF;Blankson,JoelN
• 通讯作者: Blankson,JoelN