How does bronchoconstriction worsen asthma?

支气管收缩如何加重哮喘？

• 批准号: nhmrc : 1145332
• 负责人: Prof Alastair Stewart
• 金额: $ 71.99万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/does-bronchoconstriction-worsen-asthma/1320427
• 关键词: How; does; bronchoconstriction; worsen; asthma

Asthma causes wheeze and shortness of breath via airway narrowing, with asthma attacks commonly caused by virus infections. We plan to investigate how airway narrowing during an asthma attack decreases the body’s ability to fight off a viral infection, causing prolonged infection, worse asthma symptoms, more airway inflammation and long-term damage within the airways. We will attempt to use current and novel treatments to reverse these problems, and improve treatment for asthma.

哮喘通过呼吸道狭窄引起喘息和呼吸急促，哮喘发作通常由病毒感染引起。我们计划研究哮喘发作期间呼吸道狭窄如何降低身体抵御病毒感染的能力，导致长期感染、更严重的哮喘症状、更多的呼吸道炎症和呼吸道内的长期损害。我们将尝试使用现有的和新的治疗方法来扭转这些问题，并改进哮喘的治疗。