UKY DENTAL COBRE: DENTAL CLINICAL RESEARCH CENTER

英国 DENTAL COBRE：牙科临床研究中心

• 批准号: 6972169
• 负责人: Michael John Novak
• 金额: $ 34.64万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-23 至 2005-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6972169
• 关键词: chronic disease /disorder; clinical research; infection; inflammation; oral bacteria

The clinical research environment at the University of Kentucky is excellent. UK currently supports training through an institutional K30 award, "Career Training in Therapeutics & Translational Research", from NIH that provides career development and mentoring opportunities for clinician-scientists interested in pursuing careers in clinical research. There are currently two full time faculty of the college of dentistry pursuing clinical research training through the K30 award. However, the K30 award does not lead to a degree but provides certification of participation in a clinical research training program. Dr. Dawson (Project 5) and Dr. Cunningham (Pilot Project 1) are integrating with this program for clinical research training. The University of Kentucky Clinical Research Organization (UKCRO) is an institutionally funded center that provides regular seminars and training opportunities for clinicians and study coordinators. In addition, the UKCRO offers regulatory assistance with grants and clinical trials, assists in subject recruitment, as well as in the training and certification of research coordinators and staff. Working closely with the UKCRO, the NIH funded General Clinical Research Center (GCRC) provides seed funding for clinical projects, as well as nursing, laboratory and statistical support. The COHR has provided the focus for developing a new research culture at the College and has been the organizational structure for acquiring new laboratory and clinical research space. These activities have enabled the College to increase its research portfolio to include NIH, HRSA, Kentucky Science and Technology Center, foundation, and private company research and education funding over the last 2 1/2 years. A major University goal is to become one of the top 20 public research institutions by 2020 and a key COHR strategy is to build a responsive, rigorous, productive clinical research unit. As a result of a donation of $750,000 from the Delta Dental Plan of Kentucky and a matching donation of $750,000 from The Commonwealth of Kentucky Research Challenge Trust Fund, an endowment has been established to support the Delta Dental Plan of Kentucky Clinical Research Center (DDKCRC). The DDKCRC occupies 2,000 sq. ft. of newly renovated space in the UKCD. Renovations were funded by the Associate Vice President for Research. The clinical research initiatives of the COHR are coordinated in the DDKCRC, by Dr. M. John Novak, B.D.S., L.D.S., M.S., Ph.D., the Associate Director of the COHR overseeing 4 hygienists/study coordinators, and a research associate clinician who manages the operations of the clinic. A primary focus of the DDKCRC is to create a research infrastructure to: 1) develop and train clinical research professionals, research coordinators, and research staff and 2) define and impact oral health disparities in rural communities of Kentucky. An initial emphasis will be on investigations to determine oral-systemic disease linkages in these rural populations, and to define biological, genetic, and socio-behavioral factors contributing to these disparities.

肯塔基州大学的临床研究环境非常好。英国目前通过机构K30奖支持培训，“治疗学和转化研究的职业培训”，由NIH为有兴趣从事临床研究的临床科学家提供职业发展和指导机会。目前，牙科学院有两名全职教师通过K30奖进行临床研究培训。然而，K30奖项并不授予学位，而是提供参与临床研究培训计划的认证。Dawson博士（项目5）和Cunningham博士（试点项目1）正在与该项目整合，以进行临床研究培训。肯塔基州大学临床研究组织（UKCRO）是一个机构资助的中心 为临床医生和研究协调员提供定期研讨会和培训机会。此外，UKCRO还提供赠款和临床试验方面的监管援助，协助招募受试者，以及培训和认证研究协调员和工作人员。与UKCRO密切合作，NIH资助的一般临床研究中心（GCRC）为临床项目提供种子资金，以及护理，实验室和统计支持。 COHR为学院发展新的研究文化提供了重点，并成为获得新的实验室和临床研究空间的组织结构。这些活动使学院能够增加其研究组合，包括NIH，HRSA，肯塔基州科学技术中心，基金会和私人公司的研究和教育资金在过去的2年半。大学的一个主要目标是到2020年成为前20名的公共研究机构之一，COHR的一个关键战略是建立一个反应迅速，严谨，富有成效的临床研究单位。由于肯塔基州三角洲牙科计划捐赠了75万美元，肯塔基州联邦研究挑战信托基金也捐赠了75万美元，因此建立了一个捐赠基金，以支持 肯塔基州临床研究中心（DDKCRC）的Delta牙科计划。九龙东铁路公司占地2，000平方米。英尺新装修的空间。翻修由研究副总裁资助。COHR的临床研究活动由DDKCRC协调，由M。约翰·诺瓦克博士L.D. S医学硕士，哲学博士、COHR的副主任监督4名药剂师/研究协调员，以及一名负责管理诊所运营的研究助理临床医生。DDKCRC的主要重点是创建一个研究基础设施：1）开发和培训临床研究专业人员，研究协调员和研究人员，2）定义和影响肯塔基州农村社区的口腔健康差异。最初的重点将是调查，以确定这些农村人口的口腔系统疾病的联系，并确定生物，遗传和社会行为因素，这些差异。