Risks of Medicines Used in Companion Animals to Urban Biodiversity

伴侣动物使用的药物对城市生物多样性的风险

• 批准号: 2605858
• 金额: --
• 依托单位: University of York
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2605858
• 关键词: Risks; Medicines; Used; Companion; Animals

Ecological impacts of companion animal pharmaceuticals have had limited consideration in the approval process despite the toxicity to exposed non-target organisms. This being due to present assumption that the benefits of the use of these pharmaceuticals override the potential wider ecotoxicological risk. However, due to evidence of the great number of cats and dogs in the UK (20 M), parasiticides from this source occur at detectable concentrations within the urban environment. This project will combine exposure modelling, TK/TD modelling of pulsed and mixture exposures and food web modelling. Landscape scale risks of these substances to biodiversity in urban environments will be characterised, with the potential to provide new frameworks for regulatory risk assessment of these detected compounds.

尽管伴侣动物药物对暴露的非目标生物体具有毒性，但在审批过程中对生态影响的考虑有限。这是由于目前的假设，即使用这些药物的好处超过了潜在的更广泛的生态毒理学风险。然而，有证据表明英国有大量猫和狗（20 M），来自该来源的杀虫剂在城市环境中的浓度可检测到。该项目将结合暴露建模、脉冲和混合暴露的 TK/TD 建模以及食物网建模。这些物质对城市环境中生物多样性的景观规模风险将被描述，并有可能为这些检测到的化合物的监管风险评估提供新的框架。