Biosocial risk factors for childhood behavior problems

描述（申请人提供）：本研究旨在探讨早期生物社会风险因素与儿童外化行为问题的关系。具体而言，该研究将研究产前健康因素如何与产后社会心理风险因素相互作用，从而诱发后来的外化行为。具体目的是：(1)评估产前生物学和产后社会心理风险因素对儿童外化行为的直接影响；(2)研究生物和社会心理风险因素对儿童外化行为的交互作用；(3)检验哪些因素介导了上述生物/社会风险因素对儿童外化行为的直接和交互影响；(4)识别导致儿童外化行为的生物和社会风险因素的具体组成部分；(5)检验与上述风险相关的内化行为与儿童内化行为易感性的中介因素之间的关系。产前生物学风险因素包括孕妇在怀孕期间吸烟和妊娠/分娩并发症。产后社会心理风险因素包括父母教养、育儿分歧、家庭暴力和家庭环境。进一步探讨认知能力和气质的中介作用。假设将在一项正在进行的前瞻性纵向研究的背景下进行测试，该研究使用结构方程模型对大约600名三岁的男女儿童进行研究。通过尝试进一步建立外化行为的早期，可改变的健康风险因素，并通过检查反社会行为的生物社会视角，提出的研究旨在说明护理专业如何潜在地影响这一重大的社会问题，并更好地为未来的预防计划提供信息。

DESCRIPTION (provided by applicant): This study aims to investigate the link between early biosocial risk factors and childhood externalizing behavior problems. Specifically, the study will examine how prenatal health factors interact with postnatal psychosocial risk factors in predisposing to later externalizing behavior. The specific aims are to: (1) assess the direct effect of prenatal biological and postnatal psychosocial risk factors on childhood externalizing behavior; (2) examine the interactive effect of biological and psychosocial risk factors on childhood externalizing behavior; (3) test what factors mediate the above direct and interactive effects of biological/social risk factors on childhood externalizing behavior; (4) identify the specific components of biological and social risk factors which give rise to childhood externalizing behavior; (5) test the relationship between internalizing behavior in relation to the above risk and mediating factors in predisposing to childhood internalizing behavior. Prenatal biological risk factors include maternal smoking during pregnancy, and pregnancy/birth complications. Postnatal psychosocial risk factors include parenting, child rearing disagreements, domestic violence, and home environment. Further, the mediating role of cognitive ability, and temperament, will also be explored. Hypotheses will be tested in the context of an ongoing prospective longitudinal study of approximately 600 three-year-old male and female children using structural equation modeling. By attempting to further establish the early, modifiable health risk factors for externalizing behavior, and by examining a biosocial perspective on antisocial behavior, the proposed study aims to illustrate how the Nursing profession can potentially impact this significant societal problem as well as better inform future prevention programs.