Modelling healing of geriatric distal femoral fracture fixation for pre-operative planning

目前对于股骨远端骨折的手术治疗和康复的最佳实践尚未达成共识。对于理想固定结构构型的研究，由于力学参数较多，结果往往相互矛盾。拟议的项目包括开发和验证股骨远端骨折手术管理的术前计划系统。将开发一个有限元模型来模拟骨折固定架结构内的力学条件，并开发一个模糊逻辑算法来模拟基于模拟力学条件的骨愈合。该系统将输入患者数据，包括骨折模式和几何形状，并模拟各种固定配置的骨折愈合时间，以确定最快愈合时间的手术和术后联合管理方案。初步研究了锁定钢板固定骨折中不同计算费用的螺钉-骨界面接触模拟模型。需要额外的工作，然而，螺杆轴螺纹的建模在计算上显得过于昂贵。描述了实验验证测试的计划方法。未来的工作，以完成和测试，以验证所建议的系统进行了描述。

There is currently no consensus on best practices in the surgical management and rehabilitation of distal femoral fractures. Research into ideal fixation construct configurations yields conflicting results due to the large number of mechanical parameters. The proposed project involves the development and validation of a pre-operative planning system for surgical management of distal femoral fractures. A finite element model will be developed to simulate the mechanical conditions within the fracture-fixator construct and a fuzzy logics algorithm will be developed to model bone healing based on the simulated mechanical conditions. The system will take patient data inputs including fracture pattern and geometry and simulate the fracture healing time for a variety of fixation configurations to identify the combination operative and post-operative management option with the fastest healing time.Preliminary work has investigated contact simulation models of varying computational expense for the screw-bone interface in locking plate fixated fractures. Additional work is required, however, modelling of the screw shaft threads appears prohibitively computationally expensive. Planned methodology for experimental validation tests are described. Future work for the completion and testing for validation of the proposed system are described.