Clinical and Bioinformatics Core

该核心将负责确定中心研究的所有参与者。该核心将确定潜在的参与者，联系他们的参与，并登记他们参加研究。核心将帮助安排预约，无论是在诊所还是在家里。他们也将招收家长。核心小组还将对每位参与者进行大量评估，并抽取血液样本进行DNA提取。核心的杜克和范德比尔特分支之间会有实质性的合作。此外，该核心将提供生物信息学支持，将所有相关的临床、病史、家族史和基因型信息作为中心收集的一部分建立数据库。在DUMC和VUMC场址已经部署的PEDIGENE@系统将被用作主要数据库系统。谱系@已经用于许多其他项目，并已进行了超过10年的现场测试。

This Core will be responsible for identifying all the participants in the studies of the Center. This core will identify potential participants, contact them for participation, and enroll them in the study. The core will help arrange appointments either in the clinics or in the home. They will also enroll parents. The Core will also perform numerous assessments on each of the participants, and draw blood samples for DNA extraction. There will be substantial coordination between the Duke and Vanderbilt arms of the Core. In addition, this Core will provide the bioinformatics support to database all the relevant clinical, medical history, family history, and genotypic information collected as part of the Center. The PEDIGENE@ system, already in place at both the DUMC and VUMC sites, will be used as the primary database system. PEDIGENE@ is already being used for numerous other projects and has been field tested for over 10 years.