Core A: Administrative Core

摘要 大量的研究中心（14个）和READD-ADSP提案的国际性质使得后勤， 监管和金融方面尤其复杂。核心A，行政核心，提供必要的 监督、协调和行政基础设施。核心A将监督监管 和财务方面的国际合作，并确保广泛的数据共享。适当的分享 收集数据和样本需要执行一些机构协议， 确保适当的IRB到位。核心A将确保所有文件均已签署，IRB 在转移样品之前已获得批准。一位经验丰富的财务总监将监督所有 财务方面，与各个核心、项目和现场PI密切互动和协作， 不同的READD-ADSP机构。核心A将协调和集成所有READD-ADSP组件， 活动在一项研究中，这种大规模、频繁的沟通是必不可少的。每半年举行一次电视会议 MPI和研究者将由核心A组织和管理。核心A将协调和组织 内部执行和外部科学咨询委员会会议。内部执行委员会 所有的多边投资者将每隔一个月举行一次会议，审查进展情况，并解决任何悬而未决的问题。外部 由具有相关专业知识的个人组成的科学咨询委员会将每年举行四次会议（一次在 人）提供反馈。核心A将为这些会议提供支持，并确保任何建议都得到落实。 切实贯彻最后，核心项目A将促进与可持续农业发展网络相关的科学界的互动， ADSP的目标以及外行公众。一种资源只有在人们意识到它的时候才是有价值的。核心A将提供帮助 调查人员通过国家/国际会议、出版物和新闻稿宣传其工作 and through通过the development发展of a website网站.该网站还将包含面向非专业受众的信息， 包括研究经费和参与机会的亮点。核心A还将与NIA接口， 随时向他们通报调查结果，并执行NIA要求的任何更改。

ABSTRACT The large number of sites (14) and the international nature of the READD-ADSP proposal make the logistical, regulatory and financial aspects particularly complex. Core A, the administrative core, provides the necessary oversight, coordination, and administrative infrastructure for this proposal. Core A will oversee the regulatory and financial aspects of our international collaboration and assure broad data sharing. The proper sharing of data and samples being collected necessitates the execution of a number of institutional agreements and assurance that the proper IRBs are in place. Core A will ensure that all documents have been signed and IRB approval has been obtained prior to the transfer of samples. An experienced Director of Finance will oversee all financial aspects, with close interaction and collaboration with the individual Core, Project and Site PIs at the different READD-ADSP institutions. Core A will coordinate and integrate all READD-ADSP components and activities. In a study this large, frequent communication is imperative. Semi-monthly video conferences of the MPIs and investigators will be organized and managed by Core A. Core A will coordinate and organize internal executive and external scientific advisory committee meetings. An internal executive committee of all the MPIs will meet every other month to review progress and address any outstanding issues. An external scientific advisory committee comprised of individuals with relevant expertise will meet four times a year (one in- person) to provide feedback. Core A will support these meetings and ensure that any recommendations are implemented. Lastly, Core A will facilitate the interaction with scientific communities relevant to READD- ADSP goals as well as the lay public. A resource is only valuable if people are aware of it. Core A will assist investigators with publicizing their work through national/international meetings, publications, and press releases and through the development of a website. The website will also contain information geared to the lay audience, including highlights of research funding and participation opportunities. Core A will also interface with NIA to keep them apprised of findings and to implement any changes that NIA requests.