Cardiovascular and Regenerative Sciences in WIMR Phase II

WIMR II 期心血管和再生科学

• 批准号: 7870773
• 负责人: Robert Neal Golden
• 金额: $ 1487.35万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-18 至 2014-10-01
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7870773
• 关键词: Area; Arts; Cancer Biology; Cardiovascular system; Clinical Sciences; Collaborations; Disease; Ensure; Floor; Institutes; Laboratories; Medical Research; Molecular Medicine; Neurosciences; Phase; Positioning Attribute; Public Health; Regenerative Medicine; Request for Proposals; Research; Research Infrastructure; Resources; Science; Surgical Specialties; Translations; Universities; Wisconsin; cost; innovation; medical schools; regenerative; square foot; vision science

DESCRIPTION (provided by applicant): This project, Cardiovascular and Regenerative Sciences in WIMR Phase II, is an integral component of the Wisconsin Institutes for Medical Research (WIMR) strategic initiative. WIMR embodies a three phase effort to broadly incorporate the research enterprise of the University of Wisconsin School of Medicine and Public Health (SMPH) into a physical and intellectual resource that ensures complete integration of basic and clinical sciences into an engine of discovery and translation, thereby facilitating innovation and application to a broad swath of disease-driven initiatives. The present C06 proposal is a subset of the WIMR Phase II project, a $134M, 266,000 gross square foot (GSF) facility comprised of seven laboratory floors constructed on top of underpinnings already completed during WIMR Phase I. The major scientific focus areas of WIMR II are the integration of neuroscience, cardiovascular science, regenerative medicine, molecular medicine, and visual science research, as well as fundamental cancer biology and regenerative medicine applications in surgical specialties. This proposal requests partial support to construct and fit-out one research floor in WIMR II focused upon cardiovascular and cardioregenerative sciences. In this proposal, we will fully build-out and equip one floor of WIMR II, providing more than 25,000 assignable square feet (ASF) of highly integrated space. As shown and discussed, shared infrastructure ensures economy of scale and further enhances collaboration. These resources are specific to the cardiovascular and cardioregenerative science positioned there. In conclusion, we propose to build-out and equip one floor of WIMR Phase II, with 25,000 ASF, at a cost of nearly $19M, with this request being $15M. This will provide state-of-the-art facilities in a highly transdisciplinary facility for at least 12 to 15 research teams.

描述（由申请人提供）：该项目，WIMR第二阶段的心血管和再生科学，是威斯康星州医学研究所（WIMR）战略计划的一个组成部分。WIMR体现了一个三阶段的努力，广泛地将医学和公共卫生（SMPH）的威斯康星州学校的大学的研究企业纳入一个物理和智力资源，确保基础和临床科学的发现和翻译引擎的完全整合，从而促进创新和应用到一个广泛的疾病驱动的举措。目前的C06提案是WIMR第二阶段项目的一个子集，该项目是一个耗资1.34亿美元，总面积为266，000平方英尺（GSF）的设施，由在WIMR第一阶段期间已经完成的基础之上建造的七个实验室楼层组成。WIMR II的主要科学重点领域是神经科学，心血管科学，再生医学，分子医学和视觉科学研究的整合，以及基础癌症生物学和外科专业的再生医学应用。该提案要求部分支持在WIMR II中建造和装修一个专注于心血管和心脏再生科学的研究楼层。在本提案中，我们将完全扩建和装备WIMR II的一层，提供超过25，000平方英尺（ASF）的高度集成空间。如图所示，共享基础设施可确保规模经济，并进一步增强协作。这些资源是特定于心血管和心脏再生科学定位在那里。总之，我们建议扩建和装备WIMR第二期的一个楼层，配备25，000 ASF，成本近1900万美元，这一要求为1500万美元。这将在高度跨学科的设施中为至少12至15个研究团队提供最先进的设施。