FACILITIES IMPROVEMENT FOR INFECTIOUS DISEASE RESEARCH

描述(由申请人提供)： 这份C06研究设施建设提案旨在改造研究设施，以增强一批结合良好的研究人员，他们使用集成模型来阐明人类传染病的基本细胞机制。最近资助了一项项目资助计划(PPG)，最近在传染病研究领域招聘了教师，这使得改善研究设施的需求成为必要。翻新的研究设施将使参与PPG的研究实验室得以整合和完全整合，解决基础设施不足的问题，并为更多的调查人员腾出研究空间。拟议的翻修是改善学院基础设施和满足未来传染病研究需要的总体目标的一部分。这些设施的翻新将通过翻新Goss实验室内8776平方英尺的空间来加强由小灵通支持的生物医学研究的进行。这个空间目前有空置的无病原体特定猫科动物栖息地，毗邻的研究实验室，灵知生命实验室，和一个过时的尸检设施。这个空间将被翻新，以创建4个宽敞的现代化研究实验室和支持空间，以及一个专门的啮齿动物表型和传染病尸检实验室。所有研究实验室，以及啮齿动物表型鉴定、传染病尸检和灵知菌衍生实验室，都被设计成与公共领域充分隔离，并有受控制的准入。该设施的总体目标是促进调查人员之间的互动，这些调查人员正被聚集在其围墙内，同时提供有效的传染病控制和安全。该项目拥有出色的机构支持和强有力的行政结构，以确保建设项目的成功和提高由小灵通资助的研究的研究生产率。

DESCRIPTION (provided by applicant): This C06 research facilities construction proposal seeks to renovate research facilities to enhance a group of well-bonded investigators that use integrated models to elucidate basic cellular mechanisms of human infectious disease. The recent funding of a program of projects grant (PPG) and recent faculty hires in the area of infectious disease research has necessitated the need for improved research facilities. The renovated research facilities will permit the consolidation and complete integration of the research laboratories involved in the PPG, address infrastructure deficits, and produce vacated research space for additional investigators. The proposed renovations are part of an overall goal to improve the infrastructure of the College and to meet future needs in infectious disease research. The facilities renovations will enhance the conduct of PHS-supported biomedical research through the renovation of 8,776 square feet of space within Goss Laboratories. This space currently contains unoccupied specific pathogen-free cat colony housing, an adjacent research laboratory, gnotobiotic life laboratory, and an outdated necropsy facility. This space will be renovated to create 4 spacious and modem research laboratories and support space, as well as a dedicated rodent phenotyping and infectious necropsy laboratory. All research laboratories, as well as the rodent phenotyping, infectious necropsy, and gnotobiotic derivation laboratories are designed to be sufficiently isolated from the public realm and have controlled access. An overall goal of the facility is to foster interaction among the investigators that are being brought together within its walls, while providing effective infectious disease control and security. The project has outstanding institutional support and a strong administrative structure to ensure success of the construction project and enhancement of research productivity of PHS-supported research.