Exploration of Cloud Solutions to Enhance Global Infectious Diseases Research Training Program Activities

探索云解决方案以加强全球传染病研究培训项目活动

• 批准号: 10828496
• 负责人: John Fitzgerald Lindo
• 金额: $ 16.38万
• 依托单位: STATE UNIVERSITY OF NEW YORK AT BUFFALO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10828496
• 关键词: Infectious Diseases Research; Training Programs

Jamaica and the Caribbean region endure cyclic epidemics of arboviral diseases transmitted by Aedes mosquitoes, including chikungunya, dengue, yellow fever, and Zika. Ministries of Health (MOH) across the region constantly monitor the spread of these viruses and conduct routine surveillance for the emergence of pandemic strains of respiratory viruses including influenza and SARS-CoV-2. The University of the West Indies (UWI) in Jamaica plays a key role in viral surveillance as it houses the National Influenza Center which provides weekly reports to the Surveillance Unit of the MOH. In addition, it has Jamaica's only Next Generation Sequencer which is used in both surveillance and research. This supplement application will support and expand the objectives of the parent grant, Global Infectious Diseases (GID) Research Training Progrsn The GID recently received a competitive renewal to train the next generation of Jamaican researchers using cutting edge methodologies. We consider that working knowledge of data migration and manipulation in a shared computational cloud environment is essential. The goal of this supplement application is to migrate virus surveillance data to the cloud to allow for deeper analysis by researchers and trainees from multiple UWI campuses and access to richer data for new research projects. The first phase will allow collaborators at University at BuffalolSUNY, UWI, and CTIS, Inc., the cloud collaborator, to meet virtually for training purposes and determine the most efficient strategy for migration of existing virus surveillance databases maintained at UWI and the MOH to the cloud. The MOH operates five surveillance sites across Jamaica from which samples from individuals with fever, rash and respiratory illness are submitted to the UWI Department of Microbiology or the National Public Health Laboratory for diagnosis. The Surveillance Unit produces a weekly epidemiological bulletin which is shared on its website, but the data are not readily available for further analysis and no additional research occurs. Data from this database are shared with the Pan American Health Organization and Caribbean Public Health Agency to publish bulletins on viral incidence. The second phase will include migration of the data, initial testing and review among the MOH-GID team, before the cloud dataset is made "live." The third phase will assess how the cloud resource was used by the MOH-GID team and the broader research community, and costs and benefits. The UWI is at the forefront of virology research and training through its graduate research programs in viral discovery in human and mosquito vectors through a collaborative network of investigators. These programs will gain from the proposed exploration of cloud solutions to enhance infectious diseases research in Jamaica.

牙买加和加勒比区域遭受着由下列媒介传播的虫媒病毒疾病的周期性流行病： 伊蚊，包括基孔肯雅热、登革热、黄热病和寨卡病毒。卫生部 (MOH)在整个地区不断监测这些病毒的传播，并进行例行的 监测呼吸道病毒大流行株的出现，包括流感， SARS-CoV-2.牙买加的西印度群岛大学（UWI）在病毒传播方面发挥着关键作用。 监测，因为它是国家流感中心的所在地，该中心每周向 卫生部监测股。此外，它还拥有牙买加唯一的下一代测序仪， 用于监视和研究。该补充应用程序将支持和扩展 全球传染病（GID）研究培训计划的目标 GID最近获得了一个竞争性的更新，以培养下一代牙买加人。 研究人员使用尖端的方法。我们认为数据的工作知识 在共享计算云环境中的迁移和操纵是必不可少的。目标 该补充应用程序的主要目的是将病毒监控数据迁移到云端，以便更深入地了解 来自多个UWI校区的研究人员和学员进行分析，并获得更丰富的数据， 新的研究项目。第一阶段将允许威斯康星大学布法罗分校的合作者， 和CTIS公司，云协作者，以虚拟方式进行培训，并确定 迁移西印度群岛大学现有病毒监测数据库的最有效策略 和MOH到云端。卫生部在牙买加设有五个监测点， 从发烧、皮疹和呼吸道疾病患者身上采集的样本被提交给西印度群岛大学 微生物科或国家公共卫生实验室进行诊断。的 监测股每周发布流行病公报，并在其网站上分享，但 这些数据不容易获得，无法进行进一步分析，也没有进行进一步的研究。数据 从这个数据库是与泛美卫生组织和加勒比公共 卫生署将发布关于病毒发病率的公告。第二阶段将包括 在制作云数据集之前，在MOH-GID团队中进行数据、初始测试和审查 "活下去。"第三阶段将评估MOH-GID团队如何使用云资源， 更广泛的研究社区，以及成本和收益。西印度群岛大学是病毒学的前沿 研究和培训，通过其研究生研究计划，在人类和 通过调查人员的协作网络，这些项目将从 提议探索云解决方案，以加强牙买加的传染病研究。