Innovations in Gastrointestinal Research and Therapy: FASEB summer conference

描述（由申请人提供）： 在R13机制下请求提供资金，以部分支持第十一届两年一度的FASEB夏季会议，该会议侧重于胃肠道生物学，题为“胃肠道Xi：胃肠道研究和治疗的创新”。“会议将于2005年8月13日至18日在科罗拉多的斯诺马斯举行。这些会议于1985年发起，已成为以小型会议形式（100-200名与会者）讨论与胃肠道健康和疾病相关的前沿研究的主要场所之一。方案组织的两个独特方面为外地提供了特殊价值。一个纲领性的目标是汇集在不同领域工作的研究人员，以允许思想的交叉施肥，因此会议涵盖了广泛的主题。这是我们所知道的对胃肠道研究做出贡献的唯一小型会议形式。九个科学会议将围绕癌症、上皮更新、炎症性肠病、发育、胃肠道病原体、离子转运、亚细胞钙信号、疾病中的上皮破坏和内胚层-间质相互作用等主题组织。第二个计划目标是积极促进基础和临床科学家之间的互动。这是通过使用每个会话来解决跨越健康的分子和细胞基础到胃肠道疾病的主题来实现的，并且再次通过小型会议形式来促进。科学家的目标是：1）在消化系统疾病和相关领域的研究前沿提供科学规划，围绕这些疾病的潜在病理生理学和提供保护的机制组织，2）在分子水平上整合信息，这些信息将阐明定义胃肠道器官水平行为的调节机制。该计划的组织，以提高经验和初级调查员（学生，研究员和教师到助理教授的职级）的参与，通过将他们纳入短期讲座的讲座计划作为一个抽象的驱动竞争的结果初级调查员演讲奖。我们的资金请求是专门支持这个奖励计划，让更多的初级研究人员积极参与该计划。

DESCRIPTION (provided by applicant): Funding is requested under the R13 mechanism in partial support for the eleventh biennial FASEB summer conference focused on gastrointestinal biology, entitled "Gl Tract XI: Innovations in Gl Research and Therapy." The meeting will be held in Snowmass Colorado on August 13-18, 2005. Initiated in 1985, these conferences have become one of the premier venues for the discussion of cutting-edge research related to gastrointestinal health and disease in a small meeting format (100-200 attendees). Two unique aspects of the programmatic organization provide special value to the field. One programmatic goal is to bring together researchers working in disparate fields to allow cross-fertilization of ideas, therefore a broad set of topics is covered at the meeting. This is the only small-meeting format of which we are aware that makes this contribution to gastrointestinal research. The nine scientific sessions will be organized around the topics of Cancer, Epithelial Renewal, Inflammatory Bowel Disease, Development, Gastrointestinal Pathogens, Ion Transport, Subcellular Calcium Signals, Epithelial Disruption in Disease, and Endoderm- Mesenchyme Interactions. The second programmatic goal is active promotion of interactions between basic and clinical scientists. This is achieved by using each session to address topics spanning the molecular and cellular basis of health to disease in the Gl tract, and again is facilitated by a small-meeting format. Scientifically, goals are to: 1) provide scientific programming at the forefront of research in digestive diseases and related areas, organized around the underlying pathophysiology of these diseases and the mechanisms that afford protection against them, and 2) to integrate information at the molecular level that will shed light on regulatory mechanisms that define the organ-level behavior of the gastrointestinal tract. The program is organized to enhance the experience and involvement of junior investigators (students, fellows, and faculty up to the rank of Assistant Professor), by incorporating them into the lecture program in short lectures as a result of an abstract-driven competition for Junior Investigator Speaker awards. Our funding request is specifically to support this award program allowing more Junior Investigators to participate actively in the program.