Gastrointestinal Response to Injury: Canada 2007

对损伤的胃肠道反应：加拿大 2007 年

• 批准号: 7406574
• 负责人: MARSHALL H MONTROSE
• 金额: $ 1.6万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-15 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7406574
• 关键词: Address; Affect; Award; Biology; Canada; Chronic; Clinical; Clinical Investigator; Colon; Colorado; Copper; Disease; Disease Outcome; Educational Grants; Environment; Exposure to; Fostering; Funding; Gastrointestinal Injury; Gastrointestinal tract structure; Genus Cola; Goals; Healed; Immune system; Industry; Inflammation; Inflammatory Bowel Diseases; Injury; Institutes; Investigation; Location; Minority Groups; Molecular; Non-Steroidal Anti-Inflammatory Agents; Oxidative Stress; Quebec; Request for Applications; Research; Research Personnel; Scientist; Series; Small Intestines; Time; Travel; Underrepresented Minority; Upper digestive tract structure; Woman; Work; base; carcinogenesis; cost; gastrointestinal; healing; microbial host; programs; repaired; response to injury; success

DESCRIPTION (provided by applicant): "Gastrointestinal Response to Injury: Canada 2007" will be the sixth in a series of meetings. The first meeting was held at Copper Mountain, Colorado in 1992, originally entitled "The Cellular and Molecular Basis of Gastroduodenal Mucosal Defense", and subsequent meetings have taken place every three years since. The fourth and fifth meeting (2001 and 2004) were held at Chateau Montebello, Quebec, Canada. These later meetings introduced a broader scope to the program, which included investigation of gastrointestinal mucosal defense in the colon and entire small intestine as well as the upper gastrointestinal tract. This format, as well as the location, enhanced the success of the series. The proposed meeting, "Gastrointestinal Response to Injury: Canada 2007", addresses important and cutting edge topics relevant to diseases affecting the entire luminal GI tract. The program includes three parts each consisting of two separate sessions. Part I examines factors regulating gastrointestinal responses to injury including 1) the mucosal barrier, and 2) the immune system. The second part, agents and mechanisms of gastrointestinal injury addresses 3) NSAIDs, oxidative stress, and other agents of mucosal injury, and 4) microbial-host interactions. Part III addresses manifestations of gut injury and potential to modulate disease outcomes in sessions on 5) healing, repair, and carcinogenesis, and 6) chronic inflammation and its clinical consequences including inflammatory bowel disease. A major goal of this meeting is to provide young scientists with a unique exposure to current research in the field of gastrointestinal responses to injury in an open environment in which they can interact formally and informally with established investigators from around the world. The meeting will also foster interactions among scientists working in different aspects of gastroenteric biology as well as those between basic and clinical investigators. For the first time since 1998, the meeting has a major sponsor (the AGA Institute), in addition to support by educational grants from industry that will support costs of the meeting including travel, meals and accommodation for 26 invited speakers and/or session chairs comprised of 8 women, 5 racial/ethnic minorities (including 2 traditionally underrepresented minorities), and 6 junior investigators. This application requests funds needed to support the costs of attendance for young trainee investigators who otherwise might not have the opportunity to attend such a meeting. The aim of this application is to obtain the funds for travel awards to facilitate the participation of young scientists in "Gastrointestinal Response to Injury: Canada 2007."

描述（由申请人提供）：“胃肠道对损伤的反应：加拿大2007年”将是一系列会议中的第六次。第一次会议于1992年在科罗拉多的铜山举行，最初的标题是“胃十二指肠粘液防御的细胞和分子基础”，此后每三年举行一次会议。第四次和第五次会议（2001年和2004年）在加拿大魁北克的蒙特贝洛城堡举行。这些后来的会议介绍了更广泛的范围，该计划，其中包括在结肠和整个小肠以及上消化道的胃肠道粘膜防御的调查。这种形式，以及位置，加强了系列的成功。拟议的会议，“胃肠道对损伤的反应：加拿大2007年”，解决了重要的和前沿的主题有关的疾病影响整个管腔胃肠道。该计划包括三个部分，每个部分由两个单独的会议组成。第一部分研究了调节胃肠道对损伤反应的因素，包括1）粘膜屏障，2）免疫系统。第二部分，胃肠道损伤的药物和机制，3）NSAID，氧化应激和其他粘膜损伤药物，和4）微生物-宿主相互作用。第三部分讨论了肠道损伤的表现和在5）愈合、修复和致癌过程中调节疾病结局的潜力，以及6）慢性炎症及其临床后果，包括炎症性肠病。本次会议的一个主要目标是为年轻科学家提供一个独特的接触到目前的研究领域的胃肠道反应损伤在一个开放的环境中，他们可以正式和非正式地互动与来自世界各地的既定调查人员。会议还将促进从事胃肠生物学不同方面工作的科学家之间的互动，以及基础和临床研究人员之间的互动。自1998年以来，会议第一次有了一个主要赞助商（阿加研究所），此外，工业界还提供教育赠款，用于支付会议费用，包括26名应邀发言者和/或会议主席的旅费、食宿费，其中包括8名妇女、5名少数种族/族裔（包括2名传统上代表人数不足的少数民族）和6名初级调查员。这项申请要求提供所需资金，以支付年轻见习调查员出席会议的费用，否则他们可能没有机会出席这种会议。此申请的目的是获得旅行奖励的资金，以促进年轻科学家参加“胃肠道对损伤的反应：加拿大2007年。"