FREE RADICALS IN MENTAL HEALTH & NEUROBIOLOGY

自由基与心理健康

• 批准号: 6893420
• 负责人: STEPHEN C BONDY
• 金额: $ 2万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-06-15 至 2006-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6893420
• 关键词: Internet; aging; cardiovascular disorder; cellular pathology; cytotoxicity; disease /disorder etiology; free radicals; health science research; interdisciplinary collaboration; international cooperation; meeting /conference /symposium; mental health; minority health professional; monograph; neural degeneration; neurobiology; neurotoxicology; pathologic process; postdoctoral investigator; predoctoral investigator

DESCRIPTION (Adapted from applicant's abstract): Free radical-based pathological processes are increasingly recognized as being a key component in the etiology of a wide variety of diseases associated with aging. A range of selective disorders are often superimposed on basal age-related events These include mental disorders, neurodegenerative disorders, cardiovascular diseases, cancer, and other less well-defined losses of cellular efficiency. In recent years, much investigation of oxidant-promoted cell damage has been conducted. Despite this growing amount of information concerning reactive oxygen and nitrogen species, there has been little effort made to integrate this body of knowledge across disciplines. The current application is designed to fill this gap by allowing comparison and discussion of results derived from several areas of medical investigation. The meeting is intended to serve as an integrative platform, and will be held in one of the world's finest conference centers, at the University of British Columbia, Vancouver, in July 2001 and the subsequent four years. objective of the meeting is to bring together participants from apparently unrelated fields to learn of each other's approaches to the study of this final common component of many age-related disorders. Such interactions will lead to the discovery of unexpected unifying concepts and set the groundwork for novel interactive approaches to clinical issues. It is intended to bring together leading authorities from differing fields, investigating various aspects of oxidative stress that underlies so many types of cell dysfunction. The colloquium will feature plenary lectures, The symposia, workshops, and poster presentations and will allow much time for informal discussion. The program is planned to bring together participants from diverse fields who would otherwise be unlikely to meet. This will allow the emergence of key analogies that can relate superficially diverse areas. By this means, such interaction is likely to accelerate the development of novel therapeutic strategies. The NIH support will foster the participation of international experts on free radical issues, and the meeting will be designed to assist in encouraging women and minority researchers to get involved in this exciting and rapidly emerging area. The fostering of the next generation of scientists by facilitating their participation is also a major intent of the meeting. The long-term support of this series of annual meetings will permit better planning for meeting organizers, attendees, students, and publishers.

描述（改编自申请人摘要）：基于自由基 病理过程越来越多地被认为是 与衰老有关的各种疾病的病因。一系列 选择性疾病通常叠加在基础年龄相关事件上， 包括精神障碍、神经变性疾病、心血管疾病 癌症和其他不太明确的细胞效率损失。近几 多年来，已经进行了许多关于氧化剂促进的细胞损伤的研究。 尽管关于活性氧和 氮物种，很少有人努力整合这一机构， 跨学科的知识。目前的应用程序旨在填补这一 通过比较和讨论来自几个领域的结果， 医学调查。会议旨在作为一个综合性的会议， 平台，并将在世界上最好的会议中心之一举行， 2001年7月，温哥华的不列颠哥伦比亚省大学，以及随后的 四年会议的目的是召集来自以下方面的与会者： 显然不相关的领域，以了解对方的研究方法， 这是许多与年龄有关的疾病的最后一个共同组成部分。这种相互作用 将导致发现意想不到的统一概念， 为临床问题的新型互动方法奠定基础。旨在 汇集来自不同领域的权威人士， 氧化应激的各个方面， 功能障碍座谈会将以全体讲座，专题讨论会， 研讨会和海报展示，并将有很多时间进行非正式讨论。 讨论该计划计划汇集来自不同国家的参与者， 否则不太可能见面的领域。这将允许出现 关键的类比，可以联系表面上不同的领域。通过这种方式， 这种相互作用可能会加速新的治疗药物的开发， 战略布局NIH的支持将促进国际社会的参与， 自由基问题专家，会议将协助 鼓励妇女和少数民族研究人员参与这一令人兴奋的， 迅速崛起的地区。培养下一代科学家， 方便他们参加也是会议的一个主要意图。的 对这一系列年度会议的长期支持将有助于更好地规划 面向会议组织者、与会者、学生和出版商。