8th International Symposium - Saga of the Genus Bordetella, 1906-2006

第八届国际研讨会 - 博德特氏菌属传奇，1906-2006

• 批准号: 7230901
• 负责人: ERIK L HEWLETT
• 金额: $ 1.2万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-22 至 2007-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7230901
• 关键词: Brucellaceae; meeting /conference /symposium; travel

Bordetella pertussis (at that time called Haemophilus pertussis) was cultured for the first time in 1906, by Bordet and Gengou, at the Institute Pasteur, and the meeting described in this proposal will include celebration of the centennial for that important event. Other early members of the genus, B. bronchiseptica and B. parapertussis, were isolated in 1912 and 1938, respectively. The incidence of pertussis is, however, now increasing in the US and other parts of the world, despite active immunization programs with wide coverage. For example, the number of reported cases in the US was almost 12,000 in 2003, an increase of six-fold since 1980 and there were 18,957 cases reported to the CDC in 2004. This is attributable, at least in part, to increases in recognition and occurrence of adolescent and adult pertussis. Beyond the original bordetellae, B. avium is an important cause of respiratory infections in birds and is responsible for tremendous economic losses for the poultry industry. In addition, several new species within the genus, such as B. hinzii, B. holmesii, B. trematum and B. petrii, are not well characterized with regard to spectrum of disease, virulence factors or pathogenesis. The genomes for B. pertussis, B. parapertussis, B. bronchiseptica and B. avium have been sequenced and the data published. This proposal is requesting support for students and post-doctoral fellows to attend the Eighth International Symposium: Saga of the Genus Bordetella, to be held in November 2006 at the Institute Pasteur, Paris. The bordetella community is an especially open and collaborative collection of scientists and it is important to assure and support attendance of trainees at meetings such as this.

百日咳杆菌（当时称为百日咳嗜血杆菌）是 1906年，由Bordet和Gengou首次培养， 巴斯德研究所，本提案所述会议将包括 纪念这一重大事件一百周年。其他早期 属的成员，B.支气管败血症和B.副百日咳， 分别于1912年和1938年被隔离。百日咳的发病率是， 然而，现在在美国和世界其他地区，尽管 积极开展免疫规划，覆盖面广。比如说 2003年，美国报告的病例数接近12,000例， 自1980年以来增加了六倍，据报有18 957例， 2004年的CDC。这至少部分归因于 青少年和成人百日咳的识别和发生。 除了最初的博德特莱，B。禽流感是导致 鸟类的呼吸道感染， 家禽业的经济损失。此外，还有几个新物种。 在属内，例如B。hinzii，B. holmesii，B.吸虫和B.彼得里， 没有很好地描述疾病谱、毒力 因素或发病机制。B的基因组。百日咳，B. B.副百日咳， B。支气管败血症和B.已经对鸟类进行了测序， 公开. 这一建议是要求支持学生和博士后 参加第八次国际专题讨论会的研究员：属的佐贺 将于2006年11月在巴黎巴斯德研究所举行。 博德特拉社区是一个特别开放和协作的 科学家的集合，重要的是要确保和支持 学员参加这样的会议。