2006 Mutagenesis Gordon Conference

2006年诱变戈登会议

• 批准号: 7158309
• 负责人: SUE JINKS-ROBERTSON
• 金额: $ 1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7158309
• 关键词: DNA repair; meeting /conference /symposium; mutagens; travel

DESCRIPTION (provided by applicant): Funds are requested to support scientists attending the Gordon Research Conference on Mutagenesis to be held August 6-11, 2006, at Salve Regina University in Rhode Island. The 2006 Mutagenesis Conference will focus on the mechanisms that generate mutagenic intermediates, on the diverse repair mechanisms that prevent the fixation of such intermediates as permanent mutations, and on the regulation of mutagenic processes. Selected speakers will be experts in the field of mutagenesis, and the meeting will serve as a forum for extensive interactions among all participants through open discussions within each morning/evening session as well as afternoon poster presentations. Attendance will be limited to 135 participants, and efforts will be made to encourage the attendance of minority groups, women, graduate students, and persons with disabilities. The conference will open on the first evening with two keynote addresses and this will be followed by eight sessions focusing on (i) the fidelity of DNA synthesis, (ii) mechanisms of microbial mutagenesis, (iii) mechanisms of lesion bypass (iv) effects of transcription on genetic stability, (v) mechanisms of programmed mutagenesis, (vi) mechanisms that generate chromosomal mutations, (vii) the regulation of mutagenic processes and (viii) the relationship between mutagenesis and human disease. The field of mutagenesis is critical to human health, with mutations initiating and facilitating the progression of a multitude of human diseases, especially cancer and neurodegenerative diseases. In addition, mutagenic processes are important in controlling host-parasite interactions, and the accumulation of oxidative damage has been implicated in aging.

描述（由申请人提供）：要求提供资金，以支持参加2006年8月6日至11日在罗得岛的Salve Regina大学举行的戈登诱变研究会议的科学家。 2006年诱变会议将集中讨论产生诱变中间体的机制、防止这种中间体固定为永久突变的各种修复机制以及诱变过程的调节。 选定的发言者将是诱变领域的专家，会议将成为所有与会者通过每天上午/晚上的公开讨论以及下午的海报展示进行广泛互动的论坛。 参加人数将限制在135人，并将努力鼓励少数群体、妇女、研究生和残疾人参加。会议将在第一个晚上开幕，有两个主题演讲，随后将有八个会议，重点是（i）DNA合成的保真度，（ii）微生物诱变的机制，（iii）病变旁路的机制，（iv）转录对遗传稳定性的影响，（v）程序诱变的机制，（vi）产生染色体突变的机制，（vii）致突变过程的调节和（viii）致突变与人类疾病之间的关系。 诱变领域对人类健康至关重要，突变引发和促进了许多人类疾病的进展，特别是癌症和神经退行性疾病。此外，致突变过程在控制宿主-寄生虫相互作用中很重要，氧化损伤的积累与衰老有关。