2006 Proteoglycans Gordon Research Conferences

2006 年蛋白多糖戈登研究会议

• 批准号: 7161496
• 负责人: ALAN C RAPRAEGER
• 金额: $ 2.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7161496
• 关键词: meeting /conference /symposium; proteoglycan; travel

DESCRIPTION (provided by applicant): The 12th Gordon Conference on Proteoglycans will be held July 9th-14th at Proctor Academy in Andover, New Hampshire, USA. The purpose of this meeting will be to bring together members of the proteoglycan research community from around the world to present and discuss the most recent discoveries in the structure, function, and genetics of proteoglycans, with particular focus on signaling in disease mechanisms. The conference will continue the leading role that it has played over the past 20 years in serving as a catalyst for growth in this research community. The proteoglycan research group includes worldwide experts in chemical, cell biological, biochemical, engineering and clinical areas from academic, government and corporate laboratories. The major themes to be covered in the program include 1) Biosynthesis and Structure of Glycosaminoglycans, 2) Structure-Activity of Glycosaminoglycans in Growth Factor and Chemokine Signaling, 3) Proteoglycan Signaling in the Musculoskeletal System, 4) Proteoglycans in Cell Signaling Mechanisms, 5) Proteoglycans in Development, 6) Proteoglycans in Injury and Inflammation, 7) Proteoglycans in Cancer, and 8) Proteoglycans in Disease Models. We have planned nine sessions with a total of 31 plenary talks, with each session chaired by a known expert in the field. The speakers for the plenary talks are chosen with the primary goal of representing the top recent findings in the field. Additionally, the conference will encourage the participation of "new faces," namely, experts from other fields or disease specialties that have discovered new roles for proteoglycans in their area of expertise, or are speakers that are newly emerging on the international stage with new strategies or insights. In addition, another 20-25 short talks will be selected from the submitted abstracts, providing speaking opportunities for conferees with new and exciting findings, to provide opportunities for newer and underrepresented investigators, and to cover topics underrepresented in the plenary talks. The talks will be supplemented by active poster sessions and discussions. In all, investigators participating in this conference will be at all levels, including investigators currently funded by NIAMS, NCI, NIDCR, NINDS, NHLBI, NIA, NIDDK, NICHD, NIGMS, NCCR and other NIH Institutes. As has been the tradition at this conference, approximately a third of the planned presentations will report novel data on the role of proteoglycans in mechanisms relevant to inflammation and arthritis and other diseases of the musculoskeletal system and bone; major emphasis will also be given to proteoglycans in the cell biology of cancer invasion and tumor angiogenesis, and diseases of the vascular system and heart, and kidney, brain, and skin. Emphasis will also be given to proteoglycan signaling mechanisms and organ development. The culmination of the meeting will be two talks focused on new methodologies of discovery and approaches for new drug design based on newly discovered mechanisms. The goal of the conference is to promote the exchange of new findings, concepts and technology related to proteoglycan research into human disease. It is anticipated that the outcome of the conference will be an enhanced understanding of numerous human diseases, including those of human development, the musculoskeletal system, nervous system, vascular system, immunity and cancer, and that this understanding will ultimately lead to the formulation of new drugs for combating these diseases.

描述(由申请人提供)： 第12届戈登蛋白多糖会议将于7月9日至14日在美国新罕布夏州安多弗的普罗科特学院举行。这次会议的目的是将来自世界各地的蛋白多糖研究社区的成员聚集在一起，介绍和讨论蛋白多糖的结构、功能和遗传学方面的最新发现，特别是疾病机制中的信号转导。这次会议将继续发挥它在过去20年中所发挥的主导作用，作为这一研究界增长的催化剂。蛋白多糖研究小组包括来自学术、政府和企业实验室的世界各地的化学、细胞生物、生化、工程和临床领域的专家。该计划将涵盖的主要主题包括1)糖胺多聚糖的生物合成和结构，2)生长因子和趋化因子信号转导中的糖胺多聚糖的结构-活性，3)肌肉骨骼系统中的蛋白多糖信号，4)细胞信号机制中的蛋白多糖，5)发育中的蛋白多糖，6)损伤和炎症中的蛋白多糖，7)癌症中的蛋白多糖，以及8)疾病模型中的蛋白多糖。我们计划举行九届会议，共举行31次全体会谈，每届会议由该领域的一名知名专家主持。选择全体会谈的发言者的主要目标是介绍该领域最新的调查结果。此外，会议将鼓励“新面孔”的参与，即来自其他领域或疾病专业的专家，他们已经发现蛋白多糖在其专业领域中的新角色，或者是国际舞台上新出现的具有新战略或见解的演讲者。此外，还将从提交的摘要中挑选另外20至25次简短的演讲，为与会者提供发言机会，提出新的令人振奋的发现，为较新的和任职人数不足的调查人员提供机会，并讨论在全体会议上代表人数不足的专题。会谈将辅之以积极的海报会议和讨论。总体而言，参加这次会议的研究人员将是所有级别的，包括目前由NIAMS、NCI、NIDCR、NINDS、NHLBI、NIA、NIDDK、NICHD、NIGMS、NCCR和其他NIH研究所资助的研究人员。按照这次会议的传统，大约三分之一的计划演讲将报告与炎症和关节炎以及其他肌肉骨骼系统和骨骼疾病相关的机制中蛋白多糖的作用；主要重点也将放在蛋白多糖在癌症侵袭和肿瘤血管生成以及血管系统和心脏、肾脏、大脑和皮肤疾病的细胞生物学中。重点也将放在蛋白多糖信号机制和器官发育上。会议的最终结果将是两次会谈，重点是新发现的发现方法和基于新发现的机制的新药设计方法。会议的目标是促进与蛋白多糖研究人类疾病相关的新发现、新概念和新技术的交流。预计这次会议的成果将是增进对许多人类疾病的认识，包括人类发育、肌肉骨骼系统、神经系统、血管系统、免疫和癌症的疾病，这种认识最终将导致研制出抗击这些疾病的新药。