9th International Workshop on "Radiation Damage to DNA"

描述（由申请人提供）：第九届国际研讨会“DNA辐射损伤”将涵盖在理解DNA辐射能量沉积的后果的最新进展。 从机械的角度来看，DNA的物理、化学和生物化学变化将与生物后果和对人类健康的影响联系在一起。 该研讨会是一系列研讨会中的第九个，物理学家，化学家和生物学家在一个高度互动和多学科的论坛上讨论和介绍他们关于DNA辐射损伤的最新发现。 该研讨会将于2006年5月14日至17日在土耳其安塔利亚的Corinthia Club Hotel Tekirova举行。 参加者的人数限制在120人，其中包括来自学术、政府和研究机构的研究生、博士后研究员以及职业中期和高级科学家。 研讨会的主题包括辐射引起的和内源性DNA损伤（直接或间接电离辐射造成的DNA损伤、低剂量和高剂量的碱基损伤和复杂损伤、低LET辐射和高LET辐射造成的成簇DNA损伤）、辐射引起的DNA自由基的物理和化学、辐射引起的DNA损伤的细胞修复（碱基损伤和链断裂的修复）、辐射诱导的DNA损伤的生物学后果、径迹结构、电荷和能量转移、微剂量测定、染色质结构在DNA损伤诱导和修复中的作用、计算系统生物学在理解DNA损伤和修复方面的作用，以及DNA损伤和修复测量方面的进展。 会议的一个重要目标将是激发跨学科思维，以及与会者之间的协同和具有挑战性的互动，促进科学知识的传播和在各个研究领域形成国际科学合作。

DESCRIPTION (provided by applicant): The 9th International Workshop on "Radiation Damage to DNA" will cover recent advances in understanding the consequences of radiation energy deposition in DNA. From a mechanistic point of view, physical, chemical and biochemical changes in DNA will be linked to biological consequences and impact on human health. This workshop is the ninth in a series of workshops where physicists, chemists and biologists meet to discuss and present their most recent findings on radiation damage to DNA in a highly interactive and multidisciplinary forum. This workshop will be held May 14-17, 2006 at the Corinthia Club Hotel Tekirova, Antalya, Turkey. The number of the participants is limited to 120, who will include graduate students, post-doctoral fellows, and mid-career and senior scientists from academic, government and research institutions. The topics of the workshop include radiation-induced and endogenous DNA damage (DNA damage by direct or indirect ionizing radiation, base damage and complex lesions at low and high doses, by low and high LET radiations, clustered DNA damage), physics and chemistry of radiation-induced DNA radicals, cellular repair of radiation-induced DNA damage (repair of base lesions and strand breaks), biological consequences of radiation-induced DNA damage, track structure, charge and energy transfer, microdosimetry, role of chromatin structure in DNA damage induction and repair, computational systems biology in understanding DNA damage and repair, and advances in measurement of DNA damage and repair. An important goal of the meeting will be stimulating interdisciplinary thinking, and synergistic and challenging interactions among the participants, contributing to dissemination of scientific knowledge and to formation of international scientific collaborations in the various research areas.