"The 1st International Conference on Osteoimmunology: Interactions of the Immune

“第一届国际骨免疫学会议：免疫的相互作用

• 批准号: 7116691
• 负责人: Joseph A Lorenzo
• 金额: $ 1.7万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7116691
• 关键词: immune system; interdisciplinary collaboration; meeting /conference /symposium; osteoclasts; skeletal system; travel

DESCRIPTION (provided by applicant): It has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone and the normal development of the hematopoietic and immune systems. In the past scientists involved in immune and bone cell investigations have rarely interacted in a significant way as these disciplines have developed independently and, for the most part, remain separate. To our knowledge, no previous scientific meeting has been convened to specifically bring together the members of both fields. The goal of the proposed meeting is to allow these scientists to interact so that new collaboration can develop and more rapid progress in understanding the relationships between the immune system and the skeletal system can be achieved. The fundamental hypothesis of the organizers is that progress in the field of osteoimmunology will be delayed unless better communication is established between bone biologists and immunologists. We believe that a primary way to enhance collaborations between scientists in these previously separate disciplines is to bring the members of both fields together at a conference in which all participants can interact freely and share ideas. The conference will be held on May 26, 2006 to June 2, 2006 in Crete, Greece.

描述(由申请人提供)：直到最近才意识到免疫系统和骨骼系统有重要的相互作用。破骨细胞是骨骼动态平衡的重要细胞介质，目前已有文献证明破骨细胞来源于造血祖细胞，而造血祖细胞也能产生免疫细胞。此外，许多最初被证明可以调节免疫细胞功能的细胞因子也被证明可以调节骨细胞并影响骨骼健康。相反，骨细胞的产物似乎对骨髓在骨骼中的植入以及造血和免疫系统的正常发展至关重要。在过去，参与免疫和骨细胞研究的科学家很少有重大的互动，因为这些学科是独立发展的，而且在大多数情况下仍然是分开的。据我们所知，以前没有召开过专门将这两个领域的成员聚集在一起的科学会议。拟议中的会议的目标是让这些科学家进行互动，以便开展新的合作，并在了解免疫系统和骨骼系统之间的关系方面取得更快的进展。组织者的基本假设是，除非骨生物学家和免疫学家之间建立更好的沟通，否则骨免疫学领域的进展将被推迟。我们认为，加强科学家在这些以前分开的学科中的合作的主要方式是将这两个领域的成员聚集在一个会议上，所有参与者都可以自由地互动和分享想法。会议将于2006年5月26日至6月2日在希腊克里特岛举行。