"The 1st International Conference on Osteoimmunology: Interactions of the Immune

“第一届国际骨免疫学会议：免疫的相互作用

• 批准号: 7116691
• 负责人: Joseph A Lorenzo
• 金额: $ 1.7万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7116691
• 关键词: immune system; interdisciplinary collaboration; meeting /conference /symposium; osteoclasts; skeletal system; travel

DESCRIPTION (provided by applicant): It has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone and the normal development of the hematopoietic and immune systems. In the past scientists involved in immune and bone cell investigations have rarely interacted in a significant way as these disciplines have developed independently and, for the most part, remain separate. To our knowledge, no previous scientific meeting has been convened to specifically bring together the members of both fields. The goal of the proposed meeting is to allow these scientists to interact so that new collaboration can develop and more rapid progress in understanding the relationships between the immune system and the skeletal system can be achieved. The fundamental hypothesis of the organizers is that progress in the field of osteoimmunology will be delayed unless better communication is established between bone biologists and immunologists. We believe that a primary way to enhance collaborations between scientists in these previously separate disciplines is to bring the members of both fields together at a conference in which all participants can interact freely and share ideas. The conference will be held on May 26, 2006 to June 2, 2006 in Crete, Greece.

描述（由申请人提供）：直到最近才意识到免疫系统和骨骼系统具有主要的相互作用。现在有充分的文献证明，破骨细胞是骨骼稳态的重要细胞介质，它源自造血前体，这些前体也会引起免疫细胞。此外，还已证明许多首先证明可以调节免疫细胞功能的细胞因子可以调节骨细胞并影响骨骼健康。相反，骨细胞的产物对于骨髓植入骨骼以及造血和免疫系统的正常发育似乎至关重要。在过去的科学家中，参与免疫细胞和骨细胞研究的科学家很少有很大的相互作用，因为这些学科已经独立发展，并且在大多数情况下仍保持分开。据我们所知，没有召集以前的科学会议来具体将两个领域的成员汇集在一起​​。拟议的会议的目的是允许这些科学家进行互动，以便可以发展新的合作，并在理解免疫系统与骨骼系统之间的关系方面更快。组织者的基本假设是，除非在骨骼生物学家和免疫学家之间建立更好的沟通，否则骨气免疫学领域的进展将被推迟。我们认为，在这些以前独立的学科中，加强科学家之间合作的主要方法是将两个领域的成员聚集在一起，在该会议上，所有参与者都可以自由互动并分享想法。会议将于2006年5月26日至2006年6月2日在希腊克里特岛举行。