How factors in early life contribute to infection risk and the long term development of cardiovascular health

感染是儿童住院的最常见原因，但尚不清楚为什么一些儿童的感染更严重。感染对动脉粥样硬化(动脉硬化)发展的长期影响也是未知的，动脉硬化是心血管疾病的根本原因。这项研究对这些重要问题进行了研究，目的是开发更好的严重感染的预测和预防，并减少其对成人心血管疾病的影响。

Infection is the commonest reason for childhood hospitalisation, but it is unknown why infection is much more severe in some children. The long-term effects of infection on the development of atherosclerosis (hardening of the arteries), the underlying cause of cardiovascular disease, is also unknown. This research investigates these important questions with the aim of developing better prediction and prevention of severe infection and reducing its impact on adult cardiovascular disease.