DEMOLITION AND ASTHMA IN CHICAGO PUBLIC HOUSING

描述(由申请人提供) 应聘者：应聘者是一名有急诊背景的医生 医学，目前在职业和环境医学方面进行培训。在……里面 短期内应聘者将获得指导现场工作的经验 研究并将开发环境哮喘方面的专业知识。此外， 应聘者将精通生物统计学和环境科学 通过正式的课程工作和实地经验的方法。在 从长远来看，候选人打算成为一名独立研究员 环境流行病学，并与医疗和公共卫生合作 同事通过预防有害物质来改善公众的健康 环境暴露，也是为了提高我们对 哮喘的发病机制。 环境：拟议的培训和研究将在 伊利诺伊大学芝加哥公共卫生学院。导师和合作伙伴- 建议项目的导师在空气污染方面拥有丰富的专业知识 监测，生物气溶胶采样和分析，市中心哮喘，哮喘小组 研究、时间序列分析和时空聚类分析。所有这些都是 知识领域在环境哮喘研究中很重要。这个 环境流行病学中心是一个发展广泛的 对前沿研究和争议的理解。教职员工， 公共卫生学院的实验室和计算机设施将 应聘者可以使用。公共卫生学院公共卫生分部 流行病学和生物统计学，以及环境和生物统计司 职业健康科学积极支持应聘者的发展 作为环境流行病学的独立研究员。 研究项目：居住在公共住房的市中心居民 增加哮喘发病率和死亡率的风险。美国的城市 各州正在拆除公共住房开发项目。这可能会增加当地 空气中颗粒物的浓度。这对哮喘的影响 严重程度尚未得到研究。拟议的项目是一项小组研究， 将评估房屋拆迁对附近哮喘严重程度的影响 公屋居民。暴露的特征将是环境 取样。研究的健康影响将是哮喘症状、最大呼气流量 心率，呼出一氧化氮，这是肺部炎症的一个指标。在……里面 为了确定接触颗粒物对健康的影响， 潜在的混杂因素和效果改进剂，如环境空气污染物， 将在时间序列中考虑花粉计数和气象因素 分析。

DESCRIPTION (provided by applicant) Candidate: The candidate is a physician with a background in emergency medicine, currently training in occupational and environmental medicine. In the short term the candidate will obtain mentored experience conducting field research and will develop expertise in environmental asthma. Additionally the candidate will become proficient in biostatistics and environmental science methodologies through formal course-work and through field experience. In the long term the candidate intends to become an independent researcher in environmental epidemiology and to collaborate with medical and public health colleagues to improve the health of the public by preventing harmful environmental exposures, and also to improve our understanding of the mechanisms of asthma. Environment: The proposed training and research will be done at the University of Illinois at Chicago School of Public Health. The mentor and co- mentor of the proposed project have substantial expertise in air pollution monitoring, bio-aerosol sampling and analysis, inner-city asthma, asthma panel studies, time series analysis, and time-space cluster analysis. All of these fields of knowledge are important in environmental asthma research. The Center for Environmental Epidemiology is a forum for developing a broad understanding of leading-edge research and controversies. The faculty, laboratories and computing facilities of the School of Public Health will be available to the candidate. The School of Public Health, the Division of Epidemiology and Biostatistics, and the Division of Environmental and Occupational Health Sciences actively support the development of the candidate as an independent researcher in environmental epidemiology. Research Project: Inner city residents living in public housing are at increased risk for asthma morbidity and mortality. Cities in the United States are demolishing public housing developments. This may increase local concentrations of airborne particulate matter. The impact of this on asthma severity has not been studied. The proposed project is a panel study that will evaluate the impact of housing demolition on asthma severity of nearby public housing residents. The exposure will be characterized by environmental sampling. Health effects studied will be asthma symptoms, peak expiratory flow rate, and exhaled nitric oxide, an indicator of pulmonary inflammation. In order to determine the health effects of the particulate matter exposure, potential confounders and effect modifiers such as ambient air pollutants, pollen counts, and meteorological factors will be considered in a time-series analysis.