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DEMOLITION AND ASTHMA IN CHICAGO PUBLIC HOUSING

芝加哥公共住房的拆除和哮喘

基本信息

批准号：
7035818
负责人：
SAMUEL DOREVITCH
金额：
$ 12.55万
依托单位：
UNIVERSITY OF ILLINOIS AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2002
资助国家：
美国
起止时间：
2002-05-02 至 2007-06-15
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant) Candidate: The candidate is a physician with a background in emergency medicine, currently training in occupational and environmental medicine. In the short term the candidate will obtain mentored experience conducting field research and will develop expertise in environmental asthma. Additionally the candidate will become proficient in biostatistics and environmental science methodologies through formal course-work and through field experience. In the long term the candidate intends to become an independent researcher in environmental epidemiology and to collaborate with medical and public health colleagues to improve the health of the public by preventing harmful environmental exposures, and also to improve our understanding of the mechanisms of asthma. Environment: The proposed training and research will be done at the University of Illinois at Chicago School of Public Health. The mentor and co- mentor of the proposed project have substantial expertise in air pollution monitoring, bio-aerosol sampling and analysis, inner-city asthma, asthma panel studies, time series analysis, and time-space cluster analysis. All of these fields of knowledge are important in environmental asthma research. The Center for Environmental Epidemiology is a forum for developing a broad understanding of leading-edge research and controversies. The faculty, laboratories and computing facilities of the School of Public Health will be available to the candidate. The School of Public Health, the Division of Epidemiology and Biostatistics, and the Division of Environmental and Occupational Health Sciences actively support the development of the candidate as an independent researcher in environmental epidemiology. Research Project: Inner city residents living in public housing are at increased risk for asthma morbidity and mortality. Cities in the United States are demolishing public housing developments. This may increase local concentrations of airborne particulate matter. The impact of this on asthma severity has not been studied. The proposed project is a panel study that will evaluate the impact of housing demolition on asthma severity of nearby public housing residents. The exposure will be characterized by environmental sampling. Health effects studied will be asthma symptoms, peak expiratory flow rate, and exhaled nitric oxide, an indicator of pulmonary inflammation. In order to determine the health effects of the particulate matter exposure, potential confounders and effect modifiers such as ambient air pollutants, pollen counts, and meteorological factors will be considered in a time-series analysis.

描述（由申请人提供）候选人：候选人是一位具有急诊科背景的医生医学，目前接受职业和环境医学培训。在短期内候选人将获得指导经验研究并将发展环境哮喘方面的专业知识。另外还有候选人将精通生物统计学和环境科学通过正式课程作业和现场经验的方法论。在从长远来看，候选人打算成为一名独立研究员环境流行病学并与医疗和公共卫生部门合作同事们通过预防有害物质来改善公众健康环境暴露，并提高我们对环境的了解哮喘的机制。环境：拟议的培训和研究将在伊利诺伊大学芝加哥公共卫生学院。导师和合作者拟议项目的导师在空气污染方面拥有丰富的专业知识监测、生物气溶胶采样和分析、市中心哮喘、哮喘小组研究、时间序列分析和时空聚类分析。所有这些知识领域在环境哮喘研究中很重要。这环境流行病学中心是一个发展广泛的论坛了解前沿研究和争议。师资队伍，公共卫生学院的实验室和计算设施将可供候选人使用。公共卫生学院，分部流行病学和生物统计学，以及环境和职业健康科学积极支持候选人的发展作为环境流行病学的独立研究员。研究项目：居住在公共住房中的内城区居民哮喘发病率和死亡率的风险增加。联合国城市各州正在拆除公共住房开发项目。这可能会增加本地空气中颗粒物的浓度。这对哮喘的影响严重程度尚未研究。拟议的项目是一项小组研究将评估房屋拆迁对附近哮喘严重程度的影响公共住房居民。暴露的特点是环境采样。研究的健康影响包括哮喘症状、呼气峰值流量率和呼出一氧化氮（肺部炎症指标）。在为了确定颗粒物暴露对健康的影响，潜在的混杂因素和影响调节因素，例如环境空气污染物，花粉计数和气象因素将按时间序列考虑分析。