Time-to-event analysis of drug court health outcomes

描述（由申请人提供）：本提案是为了申请指导临床科学家奖（K23）而提交的，该奖项旨在促进Randall Brown博士作为药物滥用治疗和药物政策研究领域的独立调查员的持续发展。 该奖项将促进布朗博士在流行病学研究方法和政策以及卫生服务研究方面获得先进的研究能力。拟议的培训计划将包括完成博士学位。在人口健康科学和广泛的个人和团体辅导。麦迪逊的威斯康星州大学为拟议的工作提供了一个特别适合的环境，因为它提供了对物质使用障碍（Mike Fleming博士和Richard Brown博士）、药物政策和项目评估（D. Paul Moberg和大卫布朗博士），流行病学研究和生存分析（F.哈维尔·涅托）。Brown博士还将参加UW临床研究者预备课程（NIH K30），该课程确保了统计学、研究设计、研究伦理、管理/领导力和科学写作等核心领域的能力。 在此期间的培训补助金，布朗博士建议进行研究，审查潜在的因素，有助于成功完成药物滥用治疗方案在戴恩县毒品法庭治疗方案（DCTP）。在DCTP中成功完成药物滥用治疗取决于对非法药物使用的戒断，因此表明健康风险降低。研究将需要使用管理数据进行回归建模和生存分析。这些数据是通过与位于威斯康星州麦迪逊的戴恩县DCTP已经建立的合作提供的。法院官员支持拟议的研究，并承诺积极参与。拟议中的研究为在刑事司法系统范围内解决一个主要的健康问题-药物滥用和依赖-带来了多学科办法的优势。从这个项目中获得的见解将产生影响（1）参与药物使用障碍药物法庭方案的罪犯的有效治疗和（2）合理的社会政策，解决那些在刑事司法系统中的药物滥用和依赖性障碍的需求。在严格研究的基础上实施政策有可能减少与吸毒和犯罪活动周期有关的健康问题的发生率。

DESCRIPTION (provided by applicant): This proposal is submitted in request for a Mentored Clinical Scientist Award (K23) geared toward the ongoing development of Dr. Randall Brown as an independent investigator in the field of substance abuse treatment and drug policy research. The award will facilitate Dr. Brown's acquisition of advanced research competencies in epidemiological research methods and policy and health services research. The proposed training program will include completion of a Ph.D. in Population Health Sciences and extensive individual and group mentoring. The University of Wisconsin, Madison offers a particularly well-suited environment for the proposed work because it provides access to accomplished researchers in substance use disorders (Dr. Mike Fleming and Dr. Richard Brown), drug policy and program evaluation (Dr. D. Paul Moberg and Dr. David Brown), and epidemiological research and survival analysis (Dr. F. Javier Nieto). Dr. Brown also will participate in the UW Clinical Investigator Preparatory Pathway (NIH K30), which assures competency in core areas of statistics, study design, research ethics, management/leadership, and scientific writing. During the period of this training grant, Dr. Brown proposes to conduct research that examines potential factors contributing to successful completion of substance abuse treatment programming in the Dane County Drug Court Treatment Program (DCTP). Successful completion of substance abuse treatment in the DCTP is contingent upon abstinence from illicit substance use and is therefore indicative of reduced health risk. The research will require regression modeling and survival analysis using administrative data. This data is available through an already established collaboration with the Dane County DCTP, located in Madison Wisconsin. The officers of the Court are supportive of the proposed research and have committed to active participation. The proposed research brings the strengths of a multidisciplinary approach to a major health problem-- substance abuse and dependence--in the context of the criminal justice system. Insights gained from this project will have implications for (1) the effective treatment of offenders participating in drug court programs with substance use disorders and (2) rational social policy addressing the needs of those with substance abuse and dependence disorders in the criminal justice system. Application of policy based upon rigorous research has the potential to reduce the incidence of health problems associated with the cycle of drug use and criminal activity.