Developing and Improving Institutional Animal Resources

开发和改善机构动物资源

• 批准号: 7082597
• 负责人: SAMUEL Corbin CARTNER
• 金额: $ 64.68万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7082597
• 关键词: allergens; animal colony; birth; success; water; water quality

DESCRIPTION (provided by applicant): This application seeks support for a Hydropac watering system for rodents and for a Gammacell 40 irradiator. Both pieces of equipment will be installed in the Research Support Building, a five-story animal facility that will open later this year. The Hydropac system will allow provision of filtered, treated water in plastic pouches to animals in individual cages. The system will provide bacteria-free water, reduce animal morbidity and mortality due to water system failures, significantly reduce costs especially those associated with labor, and ensure availability of high-quality water in emergency situations. Because pouches will be distributed to the other facilities on campus where rodents are housed, over 120 federally-funded investigators (representing over $260 million dollars in research funding) will benefit from this system. The Gammacell 40 irradiator will provide a dedicated, animal irradiator maintained within an animal facility. The availability of a biosafety cabinet adjacent to the unit will allow animals to be transferred between filtered cages and filtered exposure chambers without exposing them to pathogens. Personnel exposure to animal allergens or infectious agents will also be minimized. In summary, this proposal contributes to our mission of providing and maintaining consistently high quality, healthy animals for UAB research, testing, and teaching program, assuring care of animals consistent with the standards of the Guide for the Care and Use of Laboratory Animals, providing a safe and healthy workplace for personnel, and containing program costs.

描述(由申请人提供)： 此应用程序寻求对啮齿类动物的HYPAC浇水系统和Gammacell 40辐照器的支持。这两件设备都将安装在研究支持大楼内，这是一座五层的动物设施，将于今年晚些时候开放。HYPAC系统将允许在单独的笼子里向动物提供经过过滤和处理的塑料袋中的水。该系统将提供无细菌的水，减少由于供水系统故障而导致的动物发病率和死亡率，显著降低成本，特别是与劳动力相关的成本，并确保在紧急情况下获得高质量的水。由于邮袋将被分发到校园内其他啮齿动物栖息地，超过120名联邦资助的调查人员(相当于超过2.6亿美元的研究资金)将受益于这一系统。Gammacell 40辐照器将提供在动物设施内维护的专用动物辐照器。该装置旁边的生物安全柜的可用性将允许动物在过滤的笼子和过滤的曝光室之间转移，而不会使它们暴露在病原体之下。人员接触动物过敏原或感染性物质也将降至最低。总之，这项建议有助于我们的使命，即为UAB的研究、测试和教学计划提供和维护始终如一的高质量、健康的动物，确保动物护理符合《实验动物护理和使用指南》的标准，为工作人员提供安全和健康的工作场所，并控制计划成本。