Finally new tools are available to combat drug resistant tuberculosis, but how do we make them work? Models to determine effective implementation strategies in Australia and our region

终于有了对抗耐药结核病的新工具，但我们如何让它们发挥作用呢？

• 批准号: nhmrc : 1195102
• 金额: $ 156.23万
• 依托单位国家: 澳大利亚
• 项目类别: Investigator Grants
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-01-01 至 2026-12-31
• 项目状态: 未结题
• 来源: https://researchdata.edu.au/finally-new-tools-australia-region/1778937
• 关键词: Finally; new; tools; available; combat

The risk of drug resistance in tuberculosis (MDR TB) is thwarting control efforts and must be addressed. Potential strategies being considered are; treating MDR TB in the latent phase, using new short-course treatment for active TB and using new vaccines. My work develops simulation models to test strategies before they are implemented, to maximise impact and avoid costly or low-impact interventions. I will examine strategies in Australia and in high burden countries in Australia’s region.

结核病耐药性风险（MDR TB）正在阻碍控制工作，必须加以解决。正在考虑的潜在战略是：在潜伏期治疗耐多药结核病，对活动性结核病采用新的短程治疗方法，并使用新的疫苗。我的工作是开发模拟模型，在实施战略之前对其进行测试，以最大限度地发挥影响，避免昂贵或低影响的干预措施。我将研究澳大利亚和澳大利亚地区高负担国家的战略。