Predictors of Living Kidney Donor Recruitment

描述（由申请人提供）：在美国，终末期肾病（ESRD）的惊人增长大大增加了对肾移植的需求，与慢性透析相比，肾移植已被证明可以降低死亡率并提高生活质量。鉴于尸体肾脏的供应有限，肾脏学家越来越多地将注意力集中在活体肾脏捐赠上。然而，关于哪些因素可以预测潜在的肾移植受者是否能够招募到活体供者的信息很少。我们的项目将包括对潜在移植受者的前瞻性队列研究。具体目的是预测ESRD患者成功招募潜在活体肾脏供体的能力。主要假设是成功招募供体的ESRD患者比不成功的招募者更了解活体供体移植的益处。问卷将用于测量暴露，如对肾移植受者结果的知识和信念，对活体移植的偏好，对伤害供者的恐惧，自我效能感和社会网络的力量。成功招募的主要结果将是在移植中心登记潜在供体进行评估。

DESCRIPTION (provided by applicant): The alarming rise of end-stage renal disease (ESRD) in the United States has greatly increased the demand for kidney transplantation, which has been shown to reduce mortality and improve quality of life compared to chronic dialysis. Given a limited supply of cadaveric kidneys, nephrologists have increasingly focused their attention on living kidney donation. Little information exists, however, on what factors predict whether potential kidney transplant recipients will be able to recruit living donors. Our project will consist of a prospective cohort study of potential transplant recipients. The specific aim is to predict the successful ability of ESRD patients to recruit potential living kidney donors. The primary hypothesis is that ESRD patients who are successful donor recruiters have greater knowledge about the benefits of living donor transplantation than unsuccessful recruiters. Questionnaires will be used to measure exposures such as knowledge and beliefs about outcomes for kidney transplant recipients, preference for a living transplant, fear of harming donors, self-efficacy, and strength of social network. The primary outcome of successful recruitment will be registration of a potential donor at a transplant center for evaluation.