Quantification of the environmental UVA exposure

环境 UVA 暴露的量化

• 批准号: 7113109
• 负责人: Michael G Kimlin
• 金额: $ 17.23万
• 依托单位: QUEENSLAND UNIVERSITY OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-20 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7113109
• 关键词: biomedical equipment development; cancer risk; environment related neoplasm /cancer; environmental exposure; glass; light adverse effect; monitoring device; radiation detector; radiation dosage; radiation protection; seasons; solar radiation; ultraviolet radiation

DESCRIPTION (provided by applicant): The incidence of skin cancer can be reduced by the minimization of exposures to UV radiation. For this to occur, a greater understanding of the solar UV exposure to humans in different environments is necessary. A personal dosimeter already exists for the measurement of the short wavelength UVB, and until recently, no dosimeter that measured the UVA waveband existed. However, we have developed and tested a prototype dosimeter to measure the longer wavelength UVA. Exposure to harmful solar UVA radiation is linked to skin cancer incidence and premature skin photoageing and wrinkling in humans. In the fight against the ravages caused to the human body by solar UV, there is a major gap in the scientific knowledge on the amount of UVA received by humans. Accordingly, this project aims to refine this working prototype dosimeter that will allow quantification of the UVA exposures. Socially and economically, this research project will aid in the creation of a sun-safe environment leading to skin cancer prevention and contribute to life-long public health benefits for the population. This project asks the following research questions: How much filtered UVA is transmitted through glass? Does the indoor filtered solar UV in the workplace contribute to UVA exposure? How much does this filtered UVA contribute to the total UV exposure of humans? Our hypothesis's are: The filtered UVA exposure received through glass is significant for skin damage; The UVA exposure depends on the angle of the glass to the sun, the solar zenith angle and the direction of the glass; Exposure to damaging UV radiation may occur when little or no UV protection is used, for example in office buildings. Specifically this project aims to: Based on a working prototype, further develop a reliable UVA dosimeter to measure the filtered UVA; Undertake a series of field measurements using the UVA dosimeter to evaluate the UV exposure inside motor vehicles, shopping malls and office buildings; Produce a database of exposures for each of these settings for each season; Disseminate the findings through publications and conferences to public health officials.

描述（由申请人提供）： 通过最小化对紫外线辐射的暴露，可以降低皮肤癌的发生率。为此，有必要在不同环境中对太阳能紫外线暴露于人类的情况有更深入的了解。用于测量短波长UVB的个人剂量表已经存在，直到最近，还没有测量UVA波段的剂量表。但是，我们已经开发并测试了原型剂量列表以测量更长的波长UVA。暴露于有害的太阳能UVA辐射与人类的皮肤癌发病率和过早的皮肤光照和皱纹有关。在与太阳能紫外线对人体造成的破坏的斗争中，科学知识对人类收到的UVA数量存在重大差距。因此，该项目旨在完善该工作原型剂型列表，以量化UVA暴露。在社会上和经济上，该研究项目将有助于创造一个可观的日晒环境，从而导致皮肤癌预防，并为人群带来终身的公共卫生益处。该项目询问以下研究问题：通过玻璃传输了多少过滤UVA？工作场所中的室内过滤太阳能紫外线会导致UVA暴露吗？该过滤的UVA有多少有助于人类的紫外线暴露？我们的假设是：通过玻璃接收的过滤UVA暴露对于皮肤损伤是显着的； UVA暴露取决于玻璃与太阳，太阳天顶角和玻璃方向的角度。当使用很少或没有紫外线保护时，例如在办公楼中，可能会发生受损的紫外线辐射。具体而言，该项目的目的是：基于工作原型，进一步开发了可靠的UVA剂量计来测量过滤后的UVA；使用UVA剂量计进行一系列现场测量，以评估汽车，购物中心和办公楼内的紫外线曝光；为每个季节为每个设置中的每一个设置生成一个数据库；通过出版物和会议向公共卫生官员传播调查结果。