Effect of Exercise on Prevention of Weight Gain

超过提供的空间，据估计，超过50%的美国成年人超重(体重指数和25公斤/平方米)。特别令人关切的是，在过去几十年中，肥胖症患病率(体重指数为30公斤/平方米)显著增加。锻炼似乎是预防和治疗一些慢性病的一种重要行为，目前公共卫生建议的锻炼是一周中大多数日子进行30分钟的中等强度活动(每周总共150分钟)。然而，目前还不清楚这种锻炼水平是否足以防止体重增加和肥胖的发展。因此，这项研究的目的是检验两种剂量的运动对预防中度超重成年人体重增加的效果。294名受试者将被招募参加这项研究。受试者年龄为18-50岁，体重指数在25.0~29.9 kg/m2之间。受试者将分3个队列招募，每个队列98名受试者。受试者将被随机分配到以下三个处理组之一：1)对照组，2)中等运动量，或3)高运动量。所有受试者将接受为期18个月的跟踪调查。对照组将每隔3个月在时事通讯中收到基本健康信息。中等强度运动组的受试者将至少进行150分钟的中等强度运动。高运动组的受试者将至少进行大约300分钟的中等强度运动。中等运动组和高运动组的受试者都将参加为期6个月的每周一次的行为会议，此后每两周参加一次，每月一次电话联系。这项研究的主要结果是体重从基线到18个月的变化。此外，受试者将在0个月和18个月时接受身体成分(使用DEXA)和心肺健康的评估。我们还将在这项研究中每隔3个月评估一次体力活动、饮食和行为改变的潜在中介因素的变化。这项研究的结果将对成年人预防体重增加的运动建议产生重大影响。表演网站========================================Section End===========================================

EXCEED THE SPACE PROVIDED, It is estimated that in excess of 50 percent of adults in the United States are overweight (body mass index >25 kg/m2). Of particular concern is the significant increase in the prevalence of obesity (body mass index >30 kg/m 2) over the past few decades. Exercise appears to be an important behavior for preventing a treating a number of chronic diseases, and the current public health recommendation for exercise is 30 minutes of moderate intensity activity on most days of the week (150 minutes per week total). However, it is unclear whether this level of exercise is adequate for preventing weight gain and the development of obesity. Therefore, the purpose of this study is to examine the effect of two doses of exercise on prevention of weight gain in moderately overweight adults. Two-hundred ninety four (294) subjects will be recruited to participate in this study. Subjects will be 18-50 years of age, with a body mass index ranging from 25.0 to 29.9 kg/m 2. Subjects will be recruited in three cohorts, with 98 subjects per cohort. Subjects will be randomly assigned to one of the following three treatment groups: 1) control, 2) moderate exercise, or 3) high exercise. All subjects will be followed for a period of 18 months. The control group will receive basic health information in a newsletter at 3 month intervals. Subjects in the moderate exercise group will progress to 150 minutes of at least moderate intensity exercise. Subjects in the high exercise group will progress to approximately 300 minutes of at least moderate intensity exercise. Subjects in both the moderate and high exercise groups will attend weekly behavioral sessions weekly for 6 months, and biweekly thereafter along with 1 telephone contact per month. The primary outcome of this study will be change in body weight from baseline to 18 months. In addition, subjects will undergo assessment of body composition (using DEXA) and cardiorespiratory fitness at 0 and 18 months. We will also assess changes in physical activity, diet, and potential mediators of change in behaviors at 3-month intervals throughout this study. This results of this study will have a significant impact on exercise recommendations for preventing weight gain in adults. PERFORMANCE SITE ========================================Section End===========================================